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本文引用的文献

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Copolymers of adenylic and 2-aminoadenylic acids. Effect of progressive changes in hydrogen bonding and stacking on interaction with poly(uridylic acid).腺苷酸与2-氨基腺苷酸的共聚物。氢键和堆积的逐步变化对与聚（尿苷酸）相互作用的影响。
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DNA and RNA oligomer thermodynamics: the effect of mismatched bases on double-helix stability.DNA和RNA寡聚物热力学：错配碱基对双螺旋稳定性的影响。
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Codon catalog usage is a genome strategy modulated for gene expressivity.密码子编目使用是一种为基因表达性而调节的基因组策略。
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The influence of the purine 2-amino group on DNA conformation and stability. Synthesis and conformational analysis of d[T(2-aminoA)]3.嘌呤2-氨基对DNA构象和稳定性的影响。d[T(2-氨基A)]3的合成与构象分析。
Nucleic Acids Res. 1982 Jul 24;10(14):4351-61. doi: 10.1093/nar/10.14.4351.
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Binding isotherms of nucleosides and polynucleotides measured by continuous ultrafiltration at constant volume: a rapid and precise technique.通过恒容连续超滤法测定核苷和多核苷酸的结合等温线：一种快速精确的技术。
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Poly(2-aminodeoxyadenylic acid): circular dichroism and thermal stability of its complexes and their relevance to phage DNA in which a is replaced by 2NH2A.聚（2-氨基脱氧腺苷酸）：其复合物的圆二色性和热稳定性及其与其中a被2NH2A取代的噬菌体DNA的相关性。
Biopolymers. 1983 Feb;22(2):597-600. doi: 10.1002/bip.360220204.
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The effect of single base-pair mismatches on the duplex stability of d(T-A-T-T-A-A-T-A-T-C-A-A-G-T-T-G) . d(C-A-A-C-T-T-G-A-T-A-T-T-A-A-T-A).单个碱基对错配 对 d(T-A-T-T-A-A-T-A-T-C-A-A-G-T-T-G) . d(C-A-A-C-T-T-G-A-T-A-T-T-A-A-T-A)双链稳定性的影响
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Molecular cloning of human adenosine deaminase gene sequences.人类腺苷脱氨酶基因序列的分子克隆
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9
Isolation of a human anti-haemophilic factor IX cDNA clone using a unique 52-base synthetic oligonucleotide probe deduced from the amino acid sequence of bovine factor IX.利用从牛凝血因子IX氨基酸序列推导出来的一段独特的52个碱基的合成寡核苷酸探针分离人抗血友病因子IX cDNA克隆。
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10
Isolation of a genomic clone for bovine pancreatic trypsin inhibitor by using a unique-sequence synthetic DNA probe.利用独特序列合成DNA探针分离牛胰蛋白酶抑制剂的基因组克隆。
Proc Natl Acad Sci U S A. 1983 Nov;80(22):6838-42. doi: 10.1073/pnas.80.22.6838.

涉及2,6-二氨基嘌呤碱基配对的热力学研究。

Thermodynamic studies of base pairing involving 2,6-diaminopurine.

作者信息

Cheong C, Tinoco I, Chollet A

机构信息

Department of Chemistry, University of California, Berkeley 94720.

出版信息

Nucleic Acids Res. 1988 Jun 10;16(11):5115-22. doi: 10.1093/nar/16.11.5115.

DOI:10.1093/nar/16.11.5115
PMID:3387218
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC336721/
Abstract

The thermal stabilities of oligodeoxyribonucleotide duplexes containing 2,6-diaminopurine (D) matched with each of the four normal DNA bases were determined by optical melting techniques. Comparison of optical melting curves yielded relative stabilities for the D-containing standard base pairs in an otherwise identical base-pair sequence. The D:T pair was found to be more stable than the A:T pair in dC3DG3:dC3TG3, as stable as the A:T in dCT3DT3G:dCA3TA3G, and less stable than the A:T in dCA3DA3G:dCT7G. The order of stabilities for X:Y in the DNA duplex dCA3XA3G:dCT3YT3G is: (A:T) greater than (T:D) congruent to (D:T) greater than or equal to (T:A) greater than (C:D) congruent to (D:A) congruent to (D:G) greater than or equal to (D:C) congruent to (G:D) congruent to (D:D) greater than or equal to (A:D). Implications of these results for design of DNA oligonucleotide probes are discussed.

摘要

通过光学熔解技术测定了含有与四种正常DNA碱基配对的2,6 - 二氨基嘌呤（D）的寡脱氧核糖核苷酸双链体的热稳定性。通过比较光学熔解曲线，得出了在其他方面相同的碱基对序列中含D的标准碱基对的相对稳定性。发现在dC3DG3:dC3TG3中，D:T对比A:T对更稳定；在dCT3DT3G:dCA3TA3G中，D:T对与A:T对一样稳定；在dCA3DA3G:dCT7G中，D:T对比A:T对不稳定。在DNA双链体dCA3XA3G:dCT3YT3G中，X:Y的稳定性顺序为：（A:T）大于（T:D）等同于（D:T）大于或等于（T:A）大于（C:D）等同于（D:A）等同于（D:G）大于或等于（D:C）等同于（G:D）等同于（D:D）大于或等于（A:D）。讨论了这些结果对DNA寡核苷酸探针设计的意义。