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基于社区的行为干预结合传统大西洋饮食对心血管代谢风险标志物的影响:一项整群随机对照试验(“GALIAT 研究”)。

Effects of a Community-Based Behavioral Intervention with a Traditional Atlantic Diet on Cardiometabolic Risk Markers: A Cluster Randomized Controlled Trial ("The GALIAT Study").

机构信息

Department of Laboratory Medicine, Complejo Hospitalario Universitario de Santiago de Compostela, 15706 Santiago de Compostela, Spain.

Research Methods Group, Health Research Institute of Santiago de Compostela, 15706 Santiago de Compostela, Spain.

出版信息

Nutrients. 2021 Apr 7;13(4):1211. doi: 10.3390/nu13041211.

Abstract

The Atlantic diet, the traditional dietary pattern in northern Portugal and northwest Spain, has been related to metabolic health and low ischemic heart disease mortality. The Galiat Study is a randomized controlled trial aimed to assess the effects of the Atlantic diet on anthropometric variables, metabolic profile, and nutritional habits. The dietary intervention was conducted in 250 families (720 adults and children) and performed at a primary care center. Over six months, families randomized to the intervention group received educational sessions, cooking classes, written supporting material, and foods that form part of the Atlantic diet, whereas those randomized to the control group followed their habitual lifestyle. 213 families (92.4%) completed the trial. Adults in the intervention group lost weight as opposed to controls who gained weight (adjusted mean difference -1.1 kg, < 0.001) and total serum cholesterol (adjusted mean difference -5.2 mg/dL, = 0.004). Significant differences in favor of the intervention were found in other anthropometric variables and low-density lipoprotein cholesterol, but changes in triglycerides, high-density lipoprotein cholesterol, inflammation markers, blood pressure, and glucose metabolism were not observed. A family-based nutritional intervention based on the Atlantic diet showed beneficial effects on adiposity and the lipid profile.

摘要

大西洋饮食,葡萄牙北部和西班牙西北部的传统饮食模式,与代谢健康和低缺血性心脏病死亡率有关。Galiat 研究是一项随机对照试验,旨在评估大西洋饮食对人体测量变量、代谢特征和营养习惯的影响。饮食干预在 250 个家庭(720 名成人和儿童)中进行,并在基层医疗中心进行。在六个月的时间里,随机分配到干预组的家庭接受了教育课程、烹饪课程、书面支持材料以及构成大西洋饮食一部分的食物,而随机分配到对照组的家庭则遵循他们的习惯生活方式。213 个家庭(92.4%)完成了试验。与对照组相比,干预组的成年人体重减轻(调整后的平均差异-1.1 公斤,<0.001),总胆固醇(调整后的平均差异-5.2 毫克/分升,=0.004)也有所下降。干预组在其他人体测量变量和低密度脂蛋白胆固醇方面也有显著的优势,但甘油三酯、高密度脂蛋白胆固醇、炎症标志物、血压和葡萄糖代谢的变化没有观察到。基于大西洋饮食的家庭营养干预显示对肥胖和血脂谱有有益的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbe4/8067574/775e6356504b/nutrients-13-01211-g001.jpg

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