CREA-Research Centre for Food and Nutrition, via Ardeatina 546, 00178 Rome, Italy.
Department of Pharmacy, University of Napoli Federico II, via D. Montesano 49, 80131 Napoli, Italy.
Int J Mol Sci. 2021 Apr 11;22(8):3938. doi: 10.3390/ijms22083938.
Many plants have been known for centuries to have medicinal importance with potential beneficial effects on health. Phytotherapeutic compounds are well known to play a globally significant role, in particular in the management and treatment of various chronic diseases. Among these, diabetes can cause long term damage to the body other than having a relevant economic burden on society being among the costliest chronic diseases. This motivated the focus of the proposed Special Issue, intended to develop and exploit the potential role of plants in the management and treatment of diabetes. The main topics included are: (i) description and use of medicinal plants for diabetes management; (ii) the elucidation and delineation of their main components, properties (anti-hyperglycaemic, hypoglicaemic, anti-infiammatory, apoptotic agents, etc.), (iii) the mechanism of action (in vitro and in vivo studies); (iv) formulation of nutraceuticals, botanicals, and dietary supplements useful as tools as an alternative or support to anti-diabetic pharmacological therapies; (v) development of new markers.
几个世纪以来，人们已经知道许多植物具有药用重要性，对健康可能有有益的影响。植物疗法化合物在全球范围内发挥着重要作用，特别是在管理和治疗各种慢性疾病方面。其中，糖尿病除了给社会带来相关的经济负担外，还会对身体造成长期损害，是最昂贵的慢性病之一。这促使人们关注拟议的专刊，旨在开发和利用植物在糖尿病管理和治疗方面的潜力。主要议题包括：(i) 描述和使用药用植物管理糖尿病；(ii) 阐明和描述其主要成分、特性（抗高血糖、低血糖、抗炎、凋亡等）；(iii) 作用机制（体外和体内研究）；(iv) 作为替代或支持抗糖尿病药物疗法的工具，开发有用的营养保健品、植物药和膳食补充剂；(v) 开发新的标志物。
