Department of Microbiology and Virology, Faculty of Natural Sciences, Comenius University in Bratislava, Ilkovičova 6, 842 15 Bratislava, Slovakia.
Department of Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences, Tehran 1449614535, Iran.
Int J Mol Sci. 2021 Apr 25;22(9):4470. doi: 10.3390/ijms22094470.
is a novel and major fungal pathogen that has triggered several outbreaks in the last decade. The few drugs available to treat fungal diseases, the fact that this yeast has a high rate of multidrug resistance and the occurrence of misleading identifications, and the ability of forming biofilms (naturally more resistant to drugs) has made treatments of infections highly difficult. This review intends to quickly illustrate the main issues in identification, available treatments and the associated mechanisms of resistance, and the novel and alternative treatment and drugs (natural and synthetic) that have been recently reported.
是一种新型的主要真菌病原体，在过去十年中引发了多次疫情。可用于治疗真菌感染的药物很少，而这种酵母具有很高的多药耐药率，并且存在误导性的鉴定，以及形成生物膜的能力（自然更能抵抗药物），这使得 感染的治疗变得非常困难。这篇综述旨在快速说明 鉴定、现有治疗方法以及相关耐药机制方面的主要问题，以及最近报道的新型和替代治疗方法和药物（天然和合成）。
