Centro de Investigación del Comportamiento Alimentario, Escuela de Nutrición y Dietética, Facultad de Farmacia, Universidad de Valparaíso, Valparaíso 2360102, Chile.
Escuela de Nutrición y Dietética, Facultad de Farmacia, Universidad de Valparaíso, Valparaíso 2360102, Chile.
Nutrients. 2021 Apr 25;13(5):1458. doi: 10.3390/nu13051458.
Blueberries are polyphenol-rich fruits with antioxidant and anti-inflammatory properties. Polyphenols from berries act by blocking digestive enzymes, reshaping gastrointestinal microbiota, and affecting the release of gastrointestinal hormones to regulate insulin dynamics and glucose management. However, most studies use fruit extracts instead of fresh fruit. We aimed to evaluate postprandial glucose management and antioxidant capacity of fresh blueberries consumed acutely or as a six-day supplementation in 10 sedentary subjects.
To evaluate the effect of acute blueberry intake, 150 g of blueberries were consumed together with 150 g of white bread by the subject and blood samples were collected at 0, 30, 60, 90 and 120 min to measure glucose, insulin, and plasma antioxidant capacity. To evaluate supplementation, 150 g of blueberries were provided daily for six days and sample collection was performed at day 7.
Acute consumption of blueberries decreased postprandial glucose area under the curve (AUC) and increased insulin levels at 15 min timepoint. Supplementation did not affect glucose levels but decreased insulin levels at 120 min. No changes in antioxidant capacity were observed.
Consumption of fresh blueberries improves postprandial glucose management presumably due to actions on the gastrointestinal tract, while supplementation improves insulin sensitivity, probably due antioxidant and anti-inflammatory effects.
蓝莓富含多酚，具有抗氧化和抗炎特性。浆果中的多酚通过阻断消化酶、重塑胃肠道微生物群以及影响胃肠道激素的释放来调节胰岛素动态和葡萄糖代谢。然而，大多数研究使用的是水果提取物，而不是新鲜水果。我们旨在评估 10 名久坐不动的受试者急性食用或连续六天补充新鲜蓝莓对餐后血糖管理和抗氧化能力的影响。
为了评估急性蓝莓摄入的影响，让受试者同时摄入 150 克蓝莓和 150 克白面包，并在 0、30、60、90 和 120 分钟采集血样，以测量血糖、胰岛素和血浆抗氧化能力。为了评估补充效果，每天提供 150 克蓝莓，共六天，并在第 7 天进行采样。
急性食用蓝莓可降低餐后血糖曲线下面积（AUC），并在 15 分钟时增加胰岛素水平。补充蓝莓不会影响血糖水平，但可在 120 分钟时降低胰岛素水平。抗氧化能力没有变化。
食用新鲜蓝莓可改善餐后血糖管理，可能是由于对胃肠道的作用，而补充蓝莓可提高胰岛素敏感性，可能是由于抗氧化和抗炎作用。
