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利用肿瘤和溶酶体靶向的有机光热剂进行癌症治疗的有效策略。

An efficient strategy for cancer therapy using a tumor- and lysosome-targeted organic photothermal agent.

机构信息

College of Chemistry, Chemical Engineering and Materials Science, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Collaborative Innovation Centre of Functionalized Probes for Chemical Imaging in Universities of Shandong, Institute of Molecular and Nano Science, Shandong Normal University, Jinan, 250014, P. R. China.

出版信息

Nanoscale. 2021 May 20;13(19):8790-8794. doi: 10.1039/d1nr01547h.

DOI:10.1039/d1nr01547h
PMID:33978028
Abstract

A dual-targeted organic photothermal agent for tumor cells and lysosomes was developed. In vitro and in vivo experiments demonstrated that it possessed low cytotoxicity, good biological compatibility, and tumor inhibitory effects.

摘要

开发了一种针对肿瘤细胞和溶酶体的双靶标有机光热剂。体外和体内实验表明，它具有低细胞毒性、良好的生物相容性和肿瘤抑制作用。

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