Institute of Analytical Chemistry, Chemo- and Biosensors, University of Regensburg, 93053, Regensburg, Germany.
Anal Bioanal Chem. 2021 Oct;413(24):6079-6099. doi: 10.1007/s00216-021-03382-9. Epub 2021 May 12.
Non-enzymatic electrochemical sensors possess superior stability and affordability in comparison to natural enzyme-based counterparts. A large variety of nanomaterials have been introduced as enzyme mimicking with appreciable sensitivity and detection limit for various analytes of which glucose and HO have been mostly investigated. The nanomaterials made from noble metal, non-noble metal, and metal composites, as well as carbon and their derivatives in various architectures, have been extensively proposed over the past years. Three-dimensional (3D) transducers especially realized from the hybrids of carbon nanomaterials either with metal-based nanocatalysts or heteroatom dopants are favorable owing to low cost, good electrical conductivity, and stability. In this critical review, we evaluate the current strategies to create such nanomaterials to serve as non-enzymatic transducers. Laser writing has emerged as a powerful tool for the next generation of devices owing to their low cost and resultant remarkable performance that are highly attractive to non-enzymatic transducers. So far, only few works have been reported, but in the coming years, more and more research on this topic is foreseeable.
相比基于天然酶的对应物，非酶电化学传感器具有优越的稳定性和可负担性。已经引入了大量的纳米材料作为酶模拟物，对于各种分析物具有可观的灵敏度和检测限，其中葡萄糖和 HO 已被广泛研究。近年来，已经广泛提出了各种结构的贵金属、非贵金属和金属复合材料以及碳及其衍生物纳米材料。由于成本低、导电性好和稳定性好，基于碳纳米材料与基于金属的纳米催化剂或杂原子掺杂剂的混合物的三维 (3D) 换能器特别受欢迎。在本评论中，我们评估了创建此类纳米材料作为非酶换能器的当前策略。由于成本低和性能显著，激光写入已成为下一代器件的强大工具，这对非酶换能器极具吸引力。到目前为止，只有少数几篇论文报道过这一方法，但在未来几年，预计会有更多关于这一主题的研究。
