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表面增强拉曼散射在生化与医学分析中的应用

Applications of Surface-Enhanced Raman Scattering in Biochemical and Medical Analysis.

作者信息

Szaniawska Aleksandra, Kudelski Andrzej

机构信息

Faculty of Chemistry, University of Warsaw, Warsaw, Poland.

出版信息

Front Chem. 2021 May 7;9:664134. doi: 10.3389/fchem.2021.664134. eCollection 2021.

Abstract

In this mini-review, we briefly describe certain recently developed applications of the surface-enhanced Raman spectroscopy (SERS) for determining various biochemically (especially medically) important species from ones as simple as hydrogen cations to those as complex as specific DNA fragments. We present a SERS analysis of species whose characterization is important to our understanding of various mechanisms in the human body and to show its potential as an alternative for methods routinely used in diagnostics and clinics. Furthermore, we explain how such SERS-based sensors operate and point out future prospects in this field.

摘要

在本综述中,我们简要描述了表面增强拉曼光谱(SERS)最近开发的某些应用,用于测定从简单的氢离子到复杂的特定DNA片段等各种生物化学(尤其是医学)上重要的物质。我们对一些物质进行了SERS分析,这些物质的表征对于我们理解人体中的各种机制以及展示其作为诊断和临床常规使用方法的替代方法的潜力很重要。此外,我们解释了这种基于SERS的传感器的工作原理,并指出了该领域的未来前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ff2/8138180/b996714c6506/fchem-09-664134-g0001.jpg

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