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颈动脉粥样硬化、超声与脂蛋白

Carotid Atherosclerosis, Ultrasound and Lipoproteins.

作者信息

Iannuzzi Arcangelo, Rubba Paolo, Gentile Marco, Mallardo Vania, Calcaterra Ilenia, Bresciani Alessandro, Covetti Giuseppe, Cuomo Gianluigi, Merone Pasquale, Di Lorenzo Anna, Alfieri Roberta, Aliberti Emilio, Giallauria Francesco, Di Minno Matteo Nicola Dario, Iannuzzo Gabriella

机构信息

Department of Medicine and Medical Specialties, A. Cardarelli Hospital, 80131 Naples, Italy.

Department of Clinical Medicine, Surgery Federico II University, 80131 Naples, Italy.

出版信息

Biomedicines. 2021 May 6;9(5):521. doi: 10.3390/biomedicines9050521.

DOI:10.3390/biomedicines9050521
PMID:34066616
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8148516/
Abstract

Carotid artery plaques are considered a measure of atherosclerosis and are associated with an increased risk of atherosclerotic cardiovascular disease, particularly ischemic strokes. Monitoring of patients with an elevated risk of stroke is critical in developing better prevention strategies. Non-invasive imaging allows us to directly see atherosclerosis in vessels and many features that are related to plaque vulnerability. A large body of evidence has demonstrated a strong correlation between some lipid parameters and carotid atherosclerosis. In this article, we review the relationship between lipids and atherosclerosis with a focus on carotid ultrasound, the most common method to estimate atherosclerotic load.

摘要

颈动脉斑块被视为动脉粥样硬化的一个指标,与动脉粥样硬化性心血管疾病风险增加相关,尤其是缺血性中风。对中风风险升高的患者进行监测对于制定更好的预防策略至关重要。非侵入性成像使我们能够直接观察血管中的动脉粥样硬化以及许多与斑块易损性相关的特征。大量证据表明,一些血脂参数与颈动脉粥样硬化之间存在密切关联。在本文中,我们重点围绕颈动脉超声这一评估动脉粥样硬化负荷最常用的方法,综述血脂与动脉粥样硬化之间的关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2ad/8148516/d098fcaff6ca/biomedicines-09-00521-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2ad/8148516/d098fcaff6ca/biomedicines-09-00521-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2ad/8148516/d098fcaff6ca/biomedicines-09-00521-g001.jpg

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J Atheroscler Thromb. 2021 May 1;28(5):435-453. doi: 10.5551/jat.RV17047. Epub 2021 Feb 13.
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Association between cumulative exposure to different lipid parameters and risk of newly developed carotid plaque.不同血脂参数累积暴露与新发颈动脉斑块风险的关系。
Stroke Vasc Neurol. 2021 Sep;6(3):359-365. doi: 10.1136/svn-2020-000430. Epub 2021 Jan 19.
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Carotid IMT and atherosclerosis: "Calling things by name".
甲状腺激素敏感性与颈动脉斑块风险之间的关联:一项基于健康体检队列的研究。
Front Endocrinol (Lausanne). 2024 Dec 11;15:1472752. doi: 10.3389/fendo.2024.1472752. eCollection 2024.
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Molecular imaging nanoprobes and their applications in atherosclerosis diagnosis.分子影像纳米探针及其在动脉粥样硬化诊断中的应用。
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An Evaluation of Plasma TNF, VEGF-A, and IL-6 Determination as a Risk Marker of Atherosclerotic Vascular Damage in Early-Onset CAD Patients.血浆肿瘤坏死因子、血管内皮生长因子-A和白细胞介素-6测定作为早发冠心病患者动脉粥样硬化血管损伤风险标志物的评估
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Serum LDL-C/HDL-C ratio and the risk of carotid plaques: a longitudinal study.血清 LDL-C/HDL-C 比值与颈动脉斑块风险:一项纵向研究。
BMC Cardiovasc Disord. 2022 Nov 24;22(1):501. doi: 10.1186/s12872-022-02942-w.
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Integrated Bioinformatics-Based Identification of Ferroptosis-Related Genes in Carotid Atherosclerosis.基于生物信息学的整合分析鉴定颈动脉粥样硬化中的铁死亡相关基因。
Dis Markers. 2022 Nov 7;2022:3379883. doi: 10.1155/2022/3379883. eCollection 2022.
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