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使用根提取物合成氧化锌纳米粒子及其对致病菌的活性。

Synthesis of Zinc Oxide Nanoparticles Using Root Extract and Their Activity against Pathogenic Bacteria.

机构信息

Laser Research Centre, Faculty of Health Sciences, University of Johannesburg, P.O. Box 17011, Doornfontein, Johannesburg 2028, South Africa.

出版信息

Molecules. 2021 May 19;26(10):3029. doi: 10.3390/molecules26103029.

DOI:10.3390/molecules26103029
PMID:34069558
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8161024/
Abstract

Recently, the biosynthesis of zinc oxide nanoparticles (ZnO NPs) from crude extracts and phytochemicals has attracted much attention. Green synthesis of NPs is cost-effective, eco-friendly, and is a promising alternative for chemical synthesis. This study involves ZnO NPs synthesis using root extract (RE) as an efficient reducing agent. The UV spectrum of RE-ZnO NPs exhibited a peak at 357 nm due to intrinsic bandgap absorption and an XRD pattern that matches the ZnO crystal structure (JCPDS card no: 36-1451). The average particle size calculated from the Debye-Scherrer equation is 11.34 nm. SEM analysis showed that the RE-ZnO NPs spherical in shape with clusters (1-100 nm). The antibacterial activity of the NPs was tested against using agar well diffusion, minimum inhibitory concentration, and bacterial growth assay. The phytochemicals facilitate the synthesis of stable ZnO NPs and showed antibacterial activity.

摘要

最近,利用粗提物和植物化学物质合成氧化锌纳米粒子(ZnO NPs)引起了广泛关注。纳米粒子的绿色合成具有成本效益高、环保的特点,是化学合成的一种有前途的替代方法。本研究采用根提取物(RE)作为高效还原剂合成 ZnO NPs。RE-ZnO NPs 的紫外光谱在 357nm 处出现峰,这归因于本征能带隙吸收,而 XRD 图谱与 ZnO 晶体结构(JCPDS 卡号:36-1451)相匹配。根据德拜-谢勒公式计算的平均粒径为 11.34nm。SEM 分析表明,RE-ZnO NPs 呈球形,有团聚体(1-100nm)。采用琼脂孔扩散法、最小抑菌浓度和细菌生长试验测试了 NPs 的抗菌活性。植物化学物质促进了稳定 ZnO NPs 的合成,并表现出抗菌活性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e48/8161024/fefe238c72a0/molecules-26-03029-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e48/8161024/2b65c28cbb5e/molecules-26-03029-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e48/8161024/e5bb9103286d/molecules-26-03029-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e48/8161024/8ae1260b3d03/molecules-26-03029-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e48/8161024/7652adbbb0a1/molecules-26-03029-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e48/8161024/4ed63e522ae4/molecules-26-03029-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e48/8161024/fefe238c72a0/molecules-26-03029-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e48/8161024/2b65c28cbb5e/molecules-26-03029-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e48/8161024/e5bb9103286d/molecules-26-03029-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e48/8161024/8ae1260b3d03/molecules-26-03029-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e48/8161024/7652adbbb0a1/molecules-26-03029-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e48/8161024/4ed63e522ae4/molecules-26-03029-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e48/8161024/fefe238c72a0/molecules-26-03029-g006.jpg

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