细菌后生元作为缓解心脏代谢疾病的有前景工具。
Bacterial Postbiotics as Promising Tools to Mitigate Cardiometabolic Diseases.
作者信息
Anhê Fernando F, Jensen Benjamin A H, Perazza Lais Rossi, Tchernof André, Schertzer Jonathan D, Marette André
机构信息
Department of Biochemistry and Biomedical Sciences, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
出版信息
J Lipid Atheroscler. 2021 May;10(2):123-129. doi: 10.12997/jla.2021.10.2.123. Epub 2021 Feb 9.
Gut microbes dictate critical features of host immunometabolism. Certain bacterial components and metabolites (termed postbiotics) mitigate cardiometabolic diseases whereas others potentiate pathological processes. In this review, we discuss key aspects related to the usefulness of bacterial-related molecules strategically positioned as promising treatment strategies for cardiometabolic diseases.
肠道微生物决定宿主免疫代谢的关键特征。某些细菌成分和代谢产物（称为后生元）可减轻心脏代谢疾病，而其他成分则会加剧病理过程。在这篇综述中，我们讨论了与细菌相关分子的效用相关的关键方面，这些分子被战略性地定位为心脏代谢疾病的有前景的治疗策略。
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