Shi Jun-Feng, Gong Qing-Long, Zhao Bo, Ma Bao-Yi, Chen Zi-Yang, Yang Yang, Sun Yu-Han, Wang Qi, Leng Xue, Zong Ying, Li Jian-Ming, Du Rui
College of Chinese Medicine Materials, Jilin Agricultural University, Changchun, China.
College of Animal Science and Technology, Jilin Agricultural University, Changchun, China.
Front Vet Sci. 2021 Jun 4;8:649252. doi: 10.3389/fvets.2021.649252. eCollection 2021.
Brucellosis is an important zoonotic disease caused by spp. Brucellosis is widely distributed in more than 160 or 170 countries around the world, where it poses a huge threat to animal husbandry and human health. About 150 million head of water buffalo, distributed across more than 40 countries worldwide, are kept for the purposes of service, milk, and meat. High incidence of spp. in buffalo has negatively affected dairy products and meat products. We searched all research related to seroprevalence of brucellosis in water buffalo anywhere in the world in PubMed, Science Direct, SpringerLink, China National Knowledge Infrastructure, Wanfang Database, and VIP Chinese Journal Databases. A total of 26 articles published from 1985 to 2020 met the final selection criteria. The overall seroprevalence of buffalo brucellosis worldwide was 9.7%. The seroprevalence before 2010 (20.8%) (95% CI: 5.6-42.2) was much higher than the seroprevalence rate from 2010 to 2020 (4.2%) (95% CI: 1.8-7.5). Subgroup analysis by feeding mode found that the point estimate of seroprevalence in stock buffalo (11.5%) (95% CI: 3.6-23.0) was higher than that in captive buffalo (10.6%) (95% CI: 4.9-18.1). Subgroup analysis by farming mode found that the seroprevalence was higher in captive-bred buffalo (10.7%) (95% CI: 6.6-15.7) than in intensively farmed buffalo (8.5) (95% CI: 0.9-22.2). The seroprevalence in buffalo living in dry lands (6.4%) (95% CI: 2.0-12.9) is greater than that in buffalo living in wetlands (5.1%) (95% CI: 1.8-10.4) ( < 0.05). The seroprevalence in female buffalo (10.1%) (95% CI: 3.4-19.7) was higher than that in male buffalo (4.4%) (95% CI: 2.0-7.4). The seroprevalence in lactating buffalo was higher than that in buffalo of other ages (26.9%) (95% CI: 1.8-66.5). Subgroup analysis by detection method found that the seroprevalence detected by the complement fixation test (27.3%) (95% CI: 0.7-70.8) was much higher than that detected by other methods. The results of this meta-analysis showed that buffalo brucellosis infection is very common in buffalo herds around the world. Although the seroprevalence of brucellosis in buffalo and humans is relatively low, serious effects upon animal husbandry and public health make it necessary to take effective control and preventive measures to control the spread of this disease.
布鲁氏菌病是由布鲁氏菌属引起的一种重要的人畜共患病。布鲁氏菌病广泛分布于世界160或170多个国家，对畜牧业和人类健康构成巨大威胁。全球40多个国家饲养着约1.5亿头水牛，用于劳役、产奶和产肉。水牛中布鲁氏菌属的高发病率对乳制品和肉制品产生了负面影响。我们在PubMed、Science Direct、SpringerLink、中国知网、万方数据库和维普中文期刊数据库中搜索了世界上任何地方与水牛布鲁氏菌病血清流行率相关的所有研究。1985年至2020年共发表了26篇文章符合最终入选标准。全球水牛布鲁氏菌病的总体血清流行率为9.7%。2010年以前的血清流行率（20.8%）（95%可信区间：5.6 - 42.2）远高于2010年至2020年的血清流行率（4.2%）（95%可信区间：1.8 - 7.5）。按饲养方式进行亚组分析发现，存栏水牛的血清流行率点估计值（11.5%）（95%可信区间：3.6 - 23.0）高于圈养水牛（10.6%）（95%可信区间：4.9 - 18.1）。按养殖方式进行亚组分析发现，圈养繁殖水牛的血清流行率（10.7%）（95%可信区间：6.6 - 15.7）高于集约化养殖水牛（8.5）（95%可信区间：0.9 - 22.2）。生活在旱地的水牛血清流行率（6.4%）（95%可信区间：2.0 - 12.9）高于生活在湿地的水牛（5.1%）（95%可信区间：1.8 - 10.4）（P<0.05）。雌性水牛的血清流行率（10.1%）（95%可信区间：3.4 - 19.7）高于雄性水牛（4.4%）（95%可信区间：2.0 - 7.4）。泌乳期水牛的血清流行率高于其他年龄段的水牛（26.9%）（95%可信区间：1.8 - 66.5）。按检测方法进行亚组分析发现，补体结合试验检测到的血清流行率（27.3%）（95%可信区间：0.7 - 70.8）远高于其他方法检测到的血清流行率。这项荟萃分析的结果表明，水牛布鲁氏菌病感染在世界各地的水牛群中非常普遍。虽然水牛和人类中布鲁氏菌病的血清流行率相对较低，但对畜牧业和公共卫生的严重影响使得有必要采取有效的控制和预防措施来控制这种疾病的传播。
