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比较 13 个国家中自我行为改变和政府法规对 COVID-19 死亡率的影响。

Comparing the impact on COVID-19 mortality of self-imposed behavior change and of government regulations across 13 countries.

机构信息

Economics Department, University of Exeter, Exeter, UK.

Department of Disease Control, London School of Hygiene & Tropical Medicine, London, UK.

出版信息

Health Serv Res. 2021 Oct;56(5):874-884. doi: 10.1111/1475-6773.13688. Epub 2021 Jun 28.

Abstract

OBJECTIVE

Countries have adopted different approaches, at different times, to reduce the transmission of coronavirus disease 2019 (COVID-19). Cross-country comparison could indicate the relative efficacy of these approaches. We assess various nonpharmaceutical interventions (NPIs), comparing the effects of voluntary behavior change and of changes enforced via official regulations, by examining their impacts on subsequent death rates.

DATA SOURCES

Secondary data on COVID-19 deaths from 13 European countries, over March-May 2020.

STUDY DESIGN

We examine two types of NPI: the introduction of government-enforced closure policies and self-imposed alteration of individual behaviors in the period prior to regulations. Our proxy for the latter is Google mobility data, which captures voluntary behavior change when disease salience is sufficiently high. The primary outcome variable is the rate of change in COVID-19 fatalities per day, 16-20 days after interventions take place. Linear multivariate regression analysis is used to evaluate impacts.

DATA COLLECTION/EXTRACTION METHODS: publicly available.

PRINCIPAL FINDINGS

Voluntarily reduced mobility, occurring prior to government policies, decreases the percent change in deaths per day by 9.2 percentage points (pp) (95% confidence interval [CI] 4.5-14.0 pp). Government closure policies decrease the percent change in deaths per day by 14.0 pp (95% CI 10.8-17.2 pp). Disaggregating government policies, the most beneficial for reducing fatality, are intercity travel restrictions, canceling public events, requiring face masks in some situations, and closing nonessential workplaces. Other sub-components, such as closing schools and imposing stay-at-home rules, show smaller and statistically insignificant impacts.

CONCLUSIONS

NPIs have substantially reduced fatalities arising from COVID-19. Importantly, the effect of voluntary behavior change is of the same order of magnitude as government-mandated regulations. These findings, including the substantial variation across dimensions of closure, have implications for the optimal targeted mix of government policies as the pandemic waxes and wanes, especially given the economic and human welfare consequences of strict regulations.

摘要

目的

各国在不同时期采取了不同的方法来降低 2019 年冠状病毒病(COVID-19)的传播。跨国比较可以表明这些方法的相对效果。我们评估了各种非药物干预措施(NPIs),通过检查它们对随后死亡率的影响,比较了自愿行为改变和通过官方法规强制实施的变化的效果。

数据来源

2020 年 3 月至 5 月期间来自 13 个欧洲国家的 COVID-19 死亡的二手数据。

研究设计

我们研究了两种类型的 NPI:政府强制实施的关闭政策的引入和在法规出台之前个人行为的自我调整。我们后者的代理是谷歌流动性数据,当疾病的显著度足够高时,它可以捕捉到自愿行为的变化。主要结果变量是干预措施实施后第 16-20 天 COVID-19 死亡率的日变化率。使用线性多元回归分析来评估影响。

数据收集/提取方法:公开可用。

主要发现

在政府政策出台之前自愿减少流动,可使每日死亡人数的变化减少 9.2 个百分点(95%置信区间 [CI] 4.5-14.0 个百分点)。政府关闭政策使每日死亡人数的变化减少 14.0 个百分点(95% CI 10.8-17.2 个百分点)。细分政府政策,对降低死亡率最有利的政策是限制城际旅行、取消公共活动、在某些情况下要求戴口罩和关闭非必要的工作场所。其他子组件,如关闭学校和实施居家令,显示出较小且无统计学意义的影响。

结论

非药物干预措施大大降低了 COVID-19 造成的死亡率。重要的是,自愿行为改变的效果与政府强制规定的效果相当。这些发现,包括关闭政策各个方面的巨大差异,对大流行的兴衰期间政府政策的最佳靶向组合具有影响,尤其是考虑到严格法规对经济和人类福利的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c970/8522569/d62599998f4f/HESR-56-874-g002.jpg

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