Hao Yan, Qiao Shichang, Zhang Li, Xu Ting, Bai Yanping, Hu Hongping, Zhang Wendong, Zhang Guojun
School of Information and Communication Engineering, North University of China, Taiyuan, China.
Department of Mathematics, School of Science, North University of China, Taiyuan, China.
Front Oncol. 2021 Jun 14;11:657560. doi: 10.3389/fonc.2021.657560. eCollection 2021.
Breast cancer (BC) is the primary threat to women's health, and early diagnosis of breast cancer is imperative. Although there are many ways to diagnose breast cancer, the gold standard is still pathological examination. In this paper, a low dimensional three-channel features based breast cancer histopathological images recognition method is proposed to achieve fast and accurate breast cancer benign and malignant recognition. Three-channel features of 10 descriptors were extracted, which are gray level co-occurrence matrix on one direction (GLCM1), gray level co-occurrence matrix on four directions (GLCM4), average pixel value of each channel (APVEC), Hu invariant moment (HIM), wavelet features, Tamura, completed local binary pattern (CLBP), local binary pattern (LBP), Gabor, histogram of oriented gradient (Hog), respectively. Then support vector machine (SVM) was used to assess their performance. Experiments on BreaKHis dataset show that GLCM1, GLCM4 and APVEC achieved the recognition accuracy of 90.2%-94.97% at the image level and 89.18%-94.24% at the patient level, which is better than many state-of-the-art methods, including many deep learning frameworks. The experimental results show that the breast cancer recognition based on high dimensional features will increase the recognition time, but the recognition accuracy is not greatly improved. Three-channel features will enhance the recognizability of the image, so as to achieve higher recognition accuracy than gray-level features.
乳腺癌是女性健康的主要威胁,乳腺癌的早期诊断势在必行。虽然有多种方法可用于诊断乳腺癌,但金标准仍是病理检查。本文提出了一种基于低维三通道特征的乳腺癌组织病理学图像识别方法,以实现快速、准确的乳腺癌良恶性识别。提取了10个描述符的三通道特征,分别为一个方向上的灰度共生矩阵(GLCM1)、四个方向上的灰度共生矩阵(GLCM4)、每个通道的平均像素值(APVEC)、Hu不变矩(HIM)、小波特征、田村特征、完备局部二值模式(CLBP)、局部二值模式(LBP)、Gabor特征、方向梯度直方图(Hog)。然后使用支持向量机(SVM)评估它们的性能。在BreaKHis数据集上的实验表明,GLCM1、GLCM4和APVEC在图像级别上的识别准确率达到90.2%-94.97%,在患者级别上达到89.18%-94.24%,优于许多包括许多深度学习框架在内的现有先进方法。实验结果表明,基于高维特征的乳腺癌识别会增加识别时间,但识别准确率并没有大幅提高。三通道特征将增强图像的可识别性,从而实现比灰度特征更高的识别准确率。