非胸腺依赖性和胸腺依赖性抗体反应的差异耐受性。
Differential tolerance of thymus-independent and thymus-dependent antibody responses.
作者信息
Tite J P, Marshall-Clarke S, Playfair J H
出版信息
Immunology. 1978 Feb;34(2):337-45.
Abstract
The effect of pre-immunization with soluble haptenated serum proteins or haptenated carbohydrates on the subsequent responses to the hapten in thymus-dependent or thymus-independent form was investigated. In certain cases both thymus-dependent and -independent responses were suppressed whilst in others a differential suppression of thymus-independent responsiveness was observed. These results are discussed in terms of B-cell subpopulations and mechanisms of tolerance induction.
摘要
研究了用可溶性半抗原化血清蛋白或半抗原化碳水化合物进行预免疫对随后以胸腺依赖性或非胸腺依赖性形式对半抗原产生反应的影响。在某些情况下，胸腺依赖性和非胸腺依赖性反应均受到抑制，而在其他情况下，则观察到对非胸腺依赖性反应性的差异性抑制。根据B细胞亚群和耐受性诱导机制对这些结果进行了讨论。
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Differential tolerance of thymus-independent and thymus-dependent antibody responses.非胸腺依赖性和胸腺依赖性抗体反应的差异耐受性。
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