Department of Radiology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Pediatr Radiol. 2022 Apr;52(4):837-846. doi: 10.1007/s00247-021-05157-x. Epub 2021 Jul 31.
Cranial US is an integral component of evaluating the neonatal brain, especially in the setting of critically ill infants and in the emergency setting, because cranial US can be performed portably at the bedside, is safe, and can be repeated whenever needed. Contrast-enhanced ultrasound (CEUS) involves intravenously injecting microbubbles to allow for improved visibility of large and small vessels to assess vascularity and is becoming a widespread technique to improve diagnostic performance of US across a broad spectrum of applications. CEUS has the potential to add value to routine brain US and become a useful adjunct to MRI in infants in need of bedside imaging. In this review we describe the basics of US contrast agents and CEUS technique, including safety considerations, and detail the potential clinical uses of brain CEUS.
头颅超声是评估新生儿脑的一个重要组成部分，特别是在危重症婴儿和紧急情况下，因为头颅超声可以在床边便携地进行，安全且可以根据需要随时重复。对比增强超声（CEUS）涉及静脉内注射微泡，以提高大血管和小血管的可视性，从而评估血管生成情况，并且正在成为一种广泛应用的技术，可提高超声在广泛应用中的诊断性能。CEUS 有可能增加常规脑超声的价值，并成为需要床边成像的婴儿中 MRI 的有用辅助手段。在这篇综述中，我们描述了超声对比剂和 CEUS 技术的基础知识，包括安全性考虑，并详细介绍了脑 CEUS 的潜在临床应用。
