Breuker Cyril, Guedj Anne Marie, Allan Mathilde, Coinus Loick, Molinari Nicolas, Chapet Nicolas, Roubille François, Le Quintrec Moglie, Duhalde Véronique, Jouglen Julien, Cestac Philippe, Kinowski Jean Marie, Faure Stéphanie, Faucanie Marie, Lohan Laura, Villiet Maxime, Altwegg Romain, Sultan Ariane
Department of Clinical Pharmacy, CHU Montpellier, University of Montpellier, 34000 Montpellier, France.
PhyMedExp, CHU Montpellier, INSERM, CNRS, University of Montpellier, 34295 Montpellier, France.
J Clin Med. 2021 Sep 1;10(17):3967. doi: 10.3390/jcm10173967.
The objective of this study was to assess the impact of the COVID-19 pandemic on patients' perceptions regarding infection risk and vaccination in subjects suffering from chronic diseases. A prospective observational multicentric study conducted from December 2020 to April 2021 in three French University Hospitals. Patients with chronic diseases were proposed to complete a questionnaire regarding the impact of the COVID-19 pandemic on infectious risk knowledge and vaccination. A total of 1151 patients were included and analyzed (62% of which were people with diabetes). The COVID-19 pandemic increased awareness of infectious risks by 19.3%, significantly more in people with diabetes (23.2%, from 54.4% to 67.0%, < 0.01) when compared to the other high-risk patients (12.5%, from 50.5% to 56.8%, = 0.06). Respectively, 30.6% and 16.5% of patients not up-to-date for pneumococcal and flu vaccines reported wanting to update their vaccination due to the COVID-19 pandemic. By contrast, the proportion of patients against vaccines increased during the COVID-19 pandemic (6.0% vs. 9.5%, < 0.01). The COVID-19 pandemic has led to a small increase in awareness regarding the risks of infection in patients with chronic diseases, including people with diabetes, but without any change in willingness to be vaccinated. This underlines the urgent need to sensibilize people with diabetes to infection risk and the importance of vaccination.
本研究的目的是评估新冠疫情对慢性病患者感染风险认知和疫苗接种观念的影响。2020年12月至2021年4月在法国三家大学医院进行了一项前瞻性观察性多中心研究。向慢性病患者发放了一份关于新冠疫情对感染风险知识和疫苗接种影响的问卷。共纳入并分析了1151例患者（其中62%为糖尿病患者）。新冠疫情使感染风险意识提高了19.3%，糖尿病患者提高幅度显著更大（23.2%，从54.4%升至67.0%，<0.01），相比之下其他高危患者提高幅度为12.5%（从50.5%升至56.8%，=0.06）。分别有30.6%和16.5%未接种肺炎球菌疫苗和流感疫苗的患者表示因新冠疫情希望更新疫苗接种。相比之下，新冠疫情期间反对接种疫苗的患者比例有所增加（6.0%对9.5%，<0.01）。新冠疫情使包括糖尿病患者在内的慢性病患者对感染风险的认知略有提高，但疫苗接种意愿没有变化。这凸显了提高糖尿病患者对感染风险的认识的紧迫性以及疫苗接种的重要性。
