Naceiri Mrabti Hanae, Doudach Latifa, El Menyiy Naoual, Bourhia Mohammed, Mohammad Salamatullah Ahmad, Reda Kachmar Mohamed, Belmehdi Omar, El Moudden Hamza, Naceiri Mrabti Nidal, Harhar Hicham, El Omari Nasreddine, Bouyahya Abdelhakim
Laboratory of Pharmacology and Toxicology, Bio Pharmaceutical and Toxicological Analysis Research Team, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, BP 6203, Rabat, Morocco.
Biomedical Engineering Department, National School of Arts and Crafts Rabat (ENSAM), Mohammed V University in Rabat, BP 6203, Rabat, Morocco.
Evid Based Complement Alternat Med. 2021 Sep 4;2021:6350035. doi: 10.1155/2021/6350035. eCollection 2021.
Boiss () is a rare medicinal and aromatic plant. It is widely used in traditional medicine to treat several diseases, including diarrhea, fever, cough, irritation, skin diseases, rheumatism, respiratory ailments, influenza, and digestion problems. In this review, we have critically summarized previous data on about its phytochemistry, botanical and geographical distribution, toxicological investigation, and pharmacological properties. Using scientific research databases such as Wiley Online, SciFinder, ScienceDirect, PubMed, SpringerLink, Web of Science, Scopus Wiley Online, and Google Scholar, the data on were collected and discussed. The presented data regrouped bioactive compounds and biological activities of . The findings of this work showed that essential oils and extracts of exhibited numerous pharmacological activities ( and ), particularly antibacterial, antifungal, antioxidant, anticancer, anti-inflammatory, insecticidal, antipyretic, antinociceptive, and immunological and behavioral effects. While toxicological studies of essential oils and extracts are lacking, modern scientific tools revealed the presence of different classes of secondary metabolites such as terpenoids, alkaloids, flavonoids, tannins, coumarins, quinones, carotenoids, and steroids. essential oils, especially from the aerial parts, exhibited potent antibacterial, antifungal, and antioxidant effects. An in-depth toxicological investigation is needed to validate the efficacy and safety of extracts and essential oils and their secondary metabolites. However, further pharmacokinetic and pharmacodynamic studies should be performed to validate its bioavailability.
博伊斯（Boiss）是一种珍稀的药用和芳香植物。它在传统医学中被广泛用于治疗多种疾病，包括腹泻、发烧、咳嗽、炎症、皮肤病、风湿病、呼吸道疾病、流感和消化问题。在本综述中，我们严格总结了此前关于其植物化学、植物学和地理分布、毒理学研究以及药理学特性的相关数据。通过使用科学研究数据库，如威利在线图书馆（Wiley Online）、化学文摘数据库（SciFinder）、科学Direct数据库、医学期刊数据库（PubMed）、施普林格链接（SpringerLink）、科学引文索引数据库（Web of Science）、Scopus威利在线图书馆以及谷歌学术搜索，收集并讨论了相关数据。所呈现的数据重新整理了博伊斯的生物活性化合物和生物活性。这项工作的研究结果表明，博伊斯的精油和提取物展现出众多药理活性（等等），特别是抗菌、抗真菌、抗氧化、抗癌、抗炎、杀虫、解热、抗伤害感受以及免疫和行为效应。虽然缺乏对博伊斯精油和提取物的毒理学研究，但现代科学工具揭示了其存在不同种类的次生代谢产物，如萜类化合物、生物碱、黄酮类化合物、单宁、香豆素、醌类、类胡萝卜素和甾体化合物。博伊斯的精油，尤其是地上部分的精油，表现出强大的抗菌、抗真菌和抗氧化作用。需要进行深入的毒理学研究以验证博伊斯提取物和精油及其次生代谢产物的功效和安全性。然而，应进一步开展药代动力学和药效学研究以验证其生物利用度。
