人类白细胞抗原-B44（HLA-B44）基因编码区的DNA序列。
DNA sequence of the coding region of the HLA-B44 gene.
作者信息
Kottmann A H, Seemann G H, Guessow H D, Roos M H
出版信息
Immunogenetics. 1986;23(6):396-400. doi: 10.1007/BF00372673.
An HLA-B44 cDNA clone was identified in a cDNA library constructed from an HLA-B44 homozygous cell line. The DNA sequence was determined and was found to contain the complete coding sequence but for (probably) the three N-terminal codons. Comparisons of the derived amino acid sequence with other HLA-A and -B locus amino acid sequences revealed four HLA-B44-specific substitutions including a new polymorphic site. Regions of strong sequence conservation for HLA-B-locus products were found at the nucleotide and amino acid levels.
在一个由HLA - B44纯合细胞系构建的cDNA文库中鉴定出一个HLA - B44 cDNA克隆。测定了其DNA序列，发现其包含完整的编码序列，但可能缺少三个N端密码子。将推导的氨基酸序列与其他HLA - A和 - B位点氨基酸序列进行比较，发现了四个HLA - B44特异性取代，包括一个新的多态性位点。在核苷酸和氨基酸水平上发现了HLA - B位点产物的强序列保守区域。
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