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职业场景和甲醛暴露评估:系统评价。

Occupational scenarios and exposure assessment to formaldehyde: A systematic review.

机构信息

Department of Public Health and Infectious Diseases, University of Rome "La Sapienza", Rome, Italy.

Department of Anatomical Histological Medical Legal Sciences and Locomotor Apparatus, University of Rome "La Sapienza", Rome, Italy.

出版信息

Indoor Air. 2022 Jan;32(1):e12949. doi: 10.1111/ina.12949. Epub 2021 Oct 27.

DOI:10.1111/ina.12949
PMID:34708443
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9298394/
Abstract

The objectives of the systematic review were to: identify the work sectors at risk for exposure to formaldehyde; investigate the procedures applied to assess occupational exposure; evaluate the reported exposure levels among the different settings. An electronic search of Pubmed, Scopus, Web of Science and ToxNet was carried out for collecting all the articles on the investigated issue published from January 1, 2004 to September 30, 2019. Forty-three papers were included in the review, and evidenced a great number of occupational scenarios at risk for formaldehyde exposure. All the included studies collected data on formaldehyde exposure levels by a similar approach: environmental and personal sampling followed by chromatographic analyses. Results ranged from not detectable values until to some mg m of airborne formaldehyde. The riskiest occupational settings for formaldehyde exposure were the gross anatomy and pathology laboratories, the hairdressing salons and some specific productive settings, such as wooden furniture factories, dairy facilities and fish hatcheries. Notice that formaldehyde, a well-known carcinogen, was recovered in air at levels higher than outdoor in almost all the studied scenarios/activities; thus, when formaldehyde cannot be removed or substituted, targeted strategies for exposure elimination or mitigation must be adopted.

摘要

本系统评价的目的是

确定接触甲醛的高风险工作领域;调查用于评估职业暴露的程序;评估不同环境下报告的暴露水平。从 2004 年 1 月 1 日至 2019 年 9 月 30 日,通过 Pubmed、Scopus、Web of Science 和 ToxNet 电子检索收集了所有关于该问题的文章。共纳入 43 篇文献,证实了许多存在甲醛暴露风险的职业场所。所有纳入的研究都采用类似的方法收集甲醛暴露水平的数据:环境和个人采样,然后进行色谱分析。结果从无法检测到的数值到空气中的甲醛达到几毫克/立方米不等。甲醛暴露风险最高的职业场所是大体解剖和病理学实验室、美发沙龙和一些特定的生产场所,如木制家具厂、奶制品厂和鱼类孵化场。值得注意的是,甲醛是一种众所周知的致癌物质,在几乎所有研究的场景/活动中,空气中的甲醛含量都高于室外;因此,当无法去除或替代甲醛时,必须采取有针对性的暴露消除或缓解策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d050/9298394/1c4a9f21edf8/INA-32-0-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d050/9298394/64cfffbb584e/INA-32-0-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d050/9298394/1c4a9f21edf8/INA-32-0-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d050/9298394/64cfffbb584e/INA-32-0-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d050/9298394/1c4a9f21edf8/INA-32-0-g001.jpg

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