钛铝钒（Ti-AlV）和钛铝铌（Ti-AlNb）种植体骨整合的比较：一项实验研究。
Comparison of osseointegration of Ti-AlV and Ti-AlNb implants: An experimental study.
作者信息
Bozoglan Alihan, Dundar Serkan
机构信息
Firat University, Faculty of Dentistry, Department of Periodontology, Elazig, Turkey.
出版信息
J Oral Biol Craniofac Res. 2021 Oct-Dec;11(4):624-627. doi: 10.1016/j.jobcr.2021.09.012. Epub 2021 Sep 17.
OBJECTIVE
In this study we aimed to investigate bone-implant connections (BICs) with Ti-AlV and Ti-AlNb alloys. Two types of surface morphology, resorbable blast material (RBM) and sandblasted and acid-etched surfaces (SLA), were used for implants.
MATERIALS AND METHODS
Thirty female Sprague Dawley rats aged 0.5-1 year were used. The rats were randomly separated into three groups: 1) Ti-AlV RBM surface ( 10), 2), Ti-AlNb RBM surface ( 10), and 3) Ti-AlNb SLA ( 10) surface implants were surgically integrated in femoral bones. The average roughness (Ra) values for these implants were 1-2 Ra. The rats were sacrificed four weeks after the surgical procedure. For each section, the BIC ratio (%) was determined as a percentage of the total implant surface that was in direct contact with the bone.
RESULTS
The BIC ratio was found to be higher in the Ti-AlNb RBM and Ti-AlNb SLA groups than in the Ti-AlV RBM group ( 0.05). There was no statistically significant difference in the BIC ratios between the Ti-AlNb RBM and Ti-AlNb SLA groups ( 0.05).
CONCLUSION
Ti-AlNb exhibited good biocompatibility with bone cells. Ti-AlNb alloy could be a candidate material for dental implant production.
目的
在本研究中，我们旨在研究钛铝钒（Ti-AlV）合金和钛铝铌（Ti-AlNb）合金与骨的植入物连接情况。植入物采用两种表面形态，即可吸收喷砂材料（RBM）表面和喷砂加酸蚀表面（SLA）。
材料与方法
使用30只年龄在0.5至1岁之间的雌性斯普拉格-道利大鼠。将大鼠随机分为三组：1）Ti-AlV RBM表面组（10只），2）Ti-AlNb RBM表面组（10只），3）Ti-AlNb SLA表面组（10只），将植入物手术植入股骨。这些植入物的平均粗糙度（Ra）值为1至2 Ra。手术后四周处死大鼠。对于每个切片，骨植入物连接率（BIC比率，%）被确定为与骨直接接触的植入物总表面的百分比。
结果
发现Ti-AlNb RBM组和Ti-AlNb SLA组的BIC比率高于Ti-AlV RBM组（P<0.05）。Ti-AlNb RBM组和Ti-AlNb SLA组之间的BIC比率无统计学显著差异（P>0.05）。
结论
Ti-AlNb与骨细胞表现出良好的生物相容性。Ti-AlNb合金可能是牙科植入物生产的候选材料。
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