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Bone healing with niobium-containing bioactive glass composition in rat femur model: A micro-CT study.含铌生物活性玻璃组合物在大鼠股骨模型中的骨愈合：微 CT 研究。
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4
Study of the Biocompatibility of Titanium-Niobium Implants by the Parameters of Their Osseointegration under Experimental Conditions.通过实验条件下钛铌植入物骨整合参数研究其生物相容性
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In vitro bioactivity evaluation of titanium and niobium metals with different surface morphologies.不同表面形态的钛和铌金属的体外生物活性评价
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钛铝钒（Ti-AlV）和钛铝铌（Ti-AlNb）种植体骨整合的比较：一项实验研究。

Comparison of osseointegration of Ti-AlV and Ti-AlNb implants: An experimental study.

作者信息

Bozoglan Alihan, Dundar Serkan

机构信息

Firat University, Faculty of Dentistry, Department of Periodontology, Elazig, Turkey.

出版信息

J Oral Biol Craniofac Res. 2021 Oct-Dec;11(4):624-627. doi: 10.1016/j.jobcr.2021.09.012. Epub 2021 Sep 17.

DOI:10.1016/j.jobcr.2021.09.012
PMID:34729345
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8546922/
Abstract

OBJECTIVE

In this study we aimed to investigate bone-implant connections (BICs) with Ti-AlV and Ti-AlNb alloys. Two types of surface morphology, resorbable blast material (RBM) and sandblasted and acid-etched surfaces (SLA), were used for implants.

MATERIALS AND METHODS

Thirty female Sprague Dawley rats aged 0.5-1 year were used. The rats were randomly separated into three groups: 1) Ti-AlV RBM surface ( 10), 2), Ti-AlNb RBM surface ( 10), and 3) Ti-AlNb SLA ( 10) surface implants were surgically integrated in femoral bones. The average roughness (Ra) values for these implants were 1-2 Ra. The rats were sacrificed four weeks after the surgical procedure. For each section, the BIC ratio (%) was determined as a percentage of the total implant surface that was in direct contact with the bone.

RESULTS

The BIC ratio was found to be higher in the Ti-AlNb RBM and Ti-AlNb SLA groups than in the Ti-AlV RBM group ( 0.05). There was no statistically significant difference in the BIC ratios between the Ti-AlNb RBM and Ti-AlNb SLA groups ( 0.05).

CONCLUSION

Ti-AlNb exhibited good biocompatibility with bone cells. Ti-AlNb alloy could be a candidate material for dental implant production.

摘要

目的

在本研究中，我们旨在研究钛铝钒（Ti-AlV）合金和钛铝铌（Ti-AlNb）合金与骨的植入物连接情况。植入物采用两种表面形态，即可吸收喷砂材料（RBM）表面和喷砂加酸蚀表面（SLA）。

材料与方法

使用30只年龄在0.5至1岁之间的雌性斯普拉格-道利大鼠。将大鼠随机分为三组：1）Ti-AlV RBM表面组（10只），2）Ti-AlNb RBM表面组（10只），3）Ti-AlNb SLA表面组（10只），将植入物手术植入股骨。这些植入物的平均粗糙度（Ra）值为1至2 Ra。手术后四周处死大鼠。对于每个切片，骨植入物连接率（BIC比率，%）被确定为与骨直接接触的植入物总表面的百分比。

结果

发现Ti-AlNb RBM组和Ti-AlNb SLA组的BIC比率高于Ti-AlV RBM组（P<0.05）。Ti-AlNb RBM组和Ti-AlNb SLA组之间的BIC比率无统计学显著差异（P>0.05）。

结论

Ti-AlNb与骨细胞表现出良好的生物相容性。Ti-AlNb合金可能是牙科植入物生产的候选材料。