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疫情各波期间苏丹患者中新冠病毒病的特征与严重程度

Characteristics and severity of COVID-19 among Sudanese patients during the waves of the pandemic.

作者信息

Abd El-Raheem Ghada Omer Hamad, Mohamed Doaa Salih Ibrahim, Yousif Maysoun Ahmed Awad, Elamin Hind Eltayeb Salih

机构信息

Pharmacy Department, American Board Certified Critical Care Clinical Pharmacist, Imperial Specialized Hospital, Alsharif Alhindi street, Khartoum, Sudan.

Emergency Department, Senior Medical Officer, Imperial Specialized Hospital, Alsharif Alhindi street, Khartoum, Sudan.

出版信息

Sci Afr. 2021 Nov;14:e01033. doi: 10.1016/j.sciaf.2021.e01033. Epub 2021 Oct 28.

Abstract

COVID-19 is associated with marked morbidity and mortality. COVID-19 symptoms ranged from mild symptoms to severe pneumonia requiring admission to intensive care unit. Imperial College reported that, this second wave in Khartoum is expected to be similar to the first wave. The aim of our study was to study the characteristics and severity of COVID-19 among Sudanese patients during the waves of the pandemic. A hospital-based analytical Cross-Sectional study assessed the characteristics of COVID-19 patients who attended Imperial Hospital since November 2020, Khartoum, Sudan. Data were collected, retrospectively, from the medical records of COVID-19 patients. The characteristics of the patients were recorded. The statistical package for social sciences (SPSS-23) was used to describe and analyze the data. Descriptive statistics and chi-square test were used; tests were considered statistically significant when  < 0.05. Of the 138 participants, 75.4% were aged above 60 years. Males were 61.6%. Severe cases were 37.7%, with higher rate in the third wave ( = 0.000). Duration of hospitalization was ≤ 5 days in 60.9% of the cases, majority were from the 2nd wave ( = 0.001). Comorbidities of COVID-19 patients were more among non-severe cases ( = 0.001). COVID-19 symptoms were more prevalent in non-severe cases. Complications were more in severe cases ( = 0.000). Odds ratio of having ischemic stroke was 6.833 [95%CI: 2.092-22.321] based on COVID-19 severity. The elderly population were the majority. More males were getting admitted. Atypical symptoms were reported beside the common symptoms. Wider multi-center studies are recommended in order to complete the big picture of COVID-19 in Sudan.

摘要

新型冠状病毒肺炎(COVID-19)与显著的发病率和死亡率相关。COVID-19的症状从轻微症状到需要入住重症监护病房的严重肺炎不等。帝国理工学院报告称,喀土穆的第二波疫情预计与第一波相似。我们研究的目的是在疫情期间研究苏丹患者中COVID-19的特征和严重程度。一项基于医院的分析性横断面研究评估了自2020年11月以来就诊于苏丹喀土穆帝国医院的COVID-19患者的特征。数据是从COVID-19患者的病历中回顾性收集的。记录了患者的特征。使用社会科学统计软件包(SPSS-23)来描述和分析数据。采用描述性统计和卡方检验;当P<0.05时,检验被认为具有统计学意义。在138名参与者中,75.4%的年龄在60岁以上。男性占61.6%。重症病例占37.7%,第三波中的比例更高(P = 0.000)。60.9%的病例住院时间≤5天,大多数来自第二波(P = 0.001)。COVID-19患者的合并症在非重症病例中更多(P = 0.001)。COVID-19症状在非重症病例中更普遍。重症病例的并发症更多(P = 0.000)。基于COVID-19的严重程度,发生缺血性中风的比值比为6.833[95%置信区间:2.092 - 22.321]。老年人群占大多数。入院的男性更多。除了常见症状外,还报告了非典型症状。建议开展更广泛的多中心研究,以全面了解苏丹的COVID-19情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57a8/8553365/4e56fe679f20/gr1_lrg.jpg

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