Nagy Ebtesam Nabil, Ibrahim Faten Mohamed, Jouda Amal Abdelfattah, Elsayed Marwa Mahmoud
Physical Therapy for Cardiovascular/Respiratory Disorder and Geriatrics Dept., Faculty of Physical Therapy, Cairo University, 7 Ahmed El zyat St., Dokki,Giza, Egypt.
Medicinal and Aromatic Plants Research Dept., National Research Center, 33 El Bohouth St., Dokki, Giza, Egypt.
J Lasers Med Sci. 2021 Jul 24;12:e39. doi: 10.34172/jlms.2021.39. eCollection 2021.
Obesity is the major pathogenesis of the non-alcoholic fatty liver disease (NAFLD). The combination of low-level laser therapy (LLLT) and Mediterranean diet (MD) is a new approach for improving liver function. 60 obese older adults (65-75 years old) with NAFLD were randomly assigned equally to two groups: a study group and a control group. The study group received LLLT and MD, while the control group followed MD only. These findings evaluated the changes in the level of liver enzymes, serum lipid profile, and anthropometric measurements (body mass index [BMI] and waist circumference [WC]) after 12 weeks of intervention. Both study and control groups showed a significant reduction in the levels of liver enzymes, serum lipid profile, BMI, and WC ( < 0.001 and < 0.01 respectively); however, the study group showed more significant results compared to the control group ( < 0.01). LLLT and MD may be considered as a treatment approach for NAFLD in older adults to improve their liver function, control dyslipidemia, and help in losing weight.
肥胖是非酒精性脂肪性肝病（NAFLD）的主要发病机制。低强度激光疗法（LLLT）与地中海饮食（MD）相结合是改善肝功能的一种新方法。60名患有NAFLD的肥胖老年人（65 - 75岁）被随机平均分为两组：研究组和对照组。研究组接受LLLT和MD，而对照组仅遵循MD。这些研究结果评估了干预12周后肝酶水平、血脂谱以及人体测量指标（体重指数[BMI]和腰围[WC]）的变化。研究组和对照组的肝酶水平、血脂谱、BMI和WC均显著降低（分别为<0.001和<0.01）；然而，与对照组相比，研究组的结果更显著（<0.01）。LLLT和MD可被视为治疗老年NAFLD患者以改善其肝功能、控制血脂异常并帮助减肥的一种治疗方法。
