Liu Chang-Min, Suo Bing, Zhang Yan
General Hospital of Heilongjiang Province Land Reclamation Bureau Infectious Disease Department, Harbin, 150088, People's Republic of China.
General Hospital of Heilongjiang Province Land Reclamation Bureau Scientific Research Section, Harbin, 150088, People's Republic of China.
Int J Gen Med. 2021 Nov 16;14:8311-8316. doi: 10.2147/IJGM.S336850. eCollection 2021.
To analyze the clinical features of patients with acute and chronic brucellosis in order to further improve the understanding of the disease.
The clinical data of 144 patients with brucellosis who were admitted to our hospital were selected for retrospective analysis and were divided into two groups: the acute phase group (n = 86) and the chronic phase group (n = 58), and the clinical characteristics of the acute and chronic phases of the disease were analyzed. The χ test was used for countable data comparisons between the two groups.
was found as the contact organism in 61 patients (70.93%) in the acute phase group and in 12 patients (20.69%) in the chronic phase group (p < 0.01). was found as the contact organism in 14 patients (16.28%) in the acute phase group and in 38 patients (65.52%) in the chronic phase group (p < 0.01). The results showed that the respective prevalence of fever, excessive sweating, splenomegaly, and lymph node enlargement were higher in the acute phase group than in the chronic phase group (p < 0.01). The respective prevalence of testicular swelling and pain were higher in the acute phase group than in the chronic phase group (p < 0.05), while the prevalence of joint and muscle pain was higher in the chronic phase group than in the acute phase group (p < 0.01).
In Harbin, two types of clinical brucellosis, acute and chronic phase, infected sheep and cattle, respectively, are endemic at the same time, which complicates diagnosis. Besides, the clinical manifestations of brucellosis are complex and diverse, and they are often misdiagnosed and mistreated, leading to serious health injuries. Therefore, it is important to improve the understanding of disease characteristics in patients with acute and chronic brucellosis.
分析急慢性布鲁氏菌病患者的临床特征，以进一步提高对该疾病的认识。
选取我院收治的144例布鲁氏菌病患者的临床资料进行回顾性分析，分为急性期组（n = 86）和慢性期组（n = 58），分析疾病急慢性期的临床特征。两组间计数资料比较采用χ检验。
急性期组61例患者（70.93%）和慢性期组12例患者（20.69%）的接触病原体为 （p < 0.01）。急性期组14例患者（16.28%）和慢性期组38例患者（65.52%）的接触病原体为 （p < 0.01）。结果显示，急性期组发热、多汗、脾肿大及淋巴结肿大的各自患病率均高于慢性期组（p < 0.01）。急性期组睾丸肿痛的各自患病率高于慢性期组（p < 0.05），而慢性期组关节和肌肉疼痛的患病率高于急性期组（p < 0.01）。
在哈尔滨，急慢性两型临床布鲁氏菌病分别感染羊和牛，同时呈地方性流行，使诊断复杂化。此外，布鲁氏菌病的临床表现复杂多样，常被误诊误治，导致严重的健康损害。因此，提高对急慢性布鲁氏菌病患者疾病特征的认识很重要。
