Kim Jei, Kim Hyun-Jung, Chang Seok Woo, Oh Soram, Kim Sun-Young, Choi Kyoung-Kyu, Kim Duck-Su, Jang Ji-Hyun
Department of Conservative Dentistry, Graduate School, Kyung Hee University, Seoul, South Korea.
Department of Conservative Dentistry, Kyung Hee University Dental Hospital, Seoul, South Korea.
Biomater Res. 2021 Nov 24;25(1):39. doi: 10.1186/s40824-021-00238-2.
The addition of bioactive glass (BG), a highly bioactive material with remineralization potential, might improve the drawback of weakening property of mineral trioxide aggregates (MTA) when it encounters with body fluid. This study aims to evaluate the effect of BG addition on physical properties of MTA.
ProRoot (MTA), and MTA with various concentrations of BG (1, 2, 5 and 10% BG/MTA) were prepared. Simulated body fluid (SBF) was used to investigate the effect of the storage solution on dentin remineralization. Prepared specimens were examined as following; the push-out bond strength to dentin, compressive strength, setting time solubility and X-ray diffraction (XRD) analysis.
The 2% BG/MTA showed higher push-out bond strengths than control group after 7 days of SBF storage. The 2% BG/MTA exhibited the highest compressive strength. Setting times were reduced in the 1 and 2% BG/MTA groups, and solubility of all experimental groups were clinically acceptable. In all groups, precipitates were observed in dentinal tubules via SEM. XRD showed the increased hydroxyapatite peaks in the 2, 5 and 10% BG/MTA groups.
It was verified that the BG-added MTA increased dentin push-out bond strength and compressive strength under SBF storage. The addition of BG did not negatively affect the MTA maturation reaction; it increased the amount of hydroxyapatite during SBF maturation.
生物活性玻璃（BG）是一种具有再矿化潜力的高生物活性材料，添加它可能改善矿物三氧化物凝聚体（MTA）遇体液时性能减弱的缺点。本研究旨在评估添加BG对MTA物理性能的影响。
制备了ProRoot（MTA）以及添加不同浓度BG（1%、2%、5%和10% BG/MTA）的MTA。使用模拟体液（SBF）研究储存溶液对牙本质再矿化的影响。对制备的标本进行如下检测：与牙本质的推出粘结强度、抗压强度、凝固时间、溶解度以及X射线衍射（XRD）分析。
在SBF储存7天后，2% BG/MTA组的推出粘结强度高于对照组。2% BG/MTA表现出最高的抗压强度。1%和2% BG/MTA组的凝固时间缩短，所有实验组的溶解度在临床上均可接受。通过扫描电子显微镜（SEM）观察到所有组的牙本质小管中均有沉淀。XRD显示2%、5%和10% BG/MTA组的羟基磷灰石峰增加。
证实了添加BG的MTA在SBF储存条件下提高了牙本质推出粘结强度和抗压强度。添加BG对MTA的成熟反应没有负面影响；在SBF成熟过程中增加了羟基磷灰石的含量。
