Kim Sungryeal, Kim Chul-Ho
Department of Otolaryngology, School of Medicine, Ajou University, Suwon 16499, Korea.
Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea.
Biomedicines. 2021 Nov 16;9(11):1700. doi: 10.3390/biomedicines9111700.
Much progress has been made since plasma was discovered in the early 1900s. The first form of plasma was thermal type, which was limited for medical use due to potential thermal damage on living cells. In the late 1900s, with the development of a nonthermal atmospheric plasma called cold plasma, profound clinical research began and 'plasma medicine' became a new area in the academic field. Plasma began to be used mainly for environmental problems, such as water purification and wastewater treatment, and subsequent research on plasma and liquid interaction led to the birth of 'plasma-activated liquid' (PAL). PAL is currently used in the fields of environment, food, agriculture, nanoparticle synthesis, analytical chemistry, and sterilization. In the medical field, PAL usage can be expanded for accessing places where direct application of plasma is difficult. In this review, recent studies with PAL will be introduced to inform researchers of the application plan and possibility of PAL in the medical field.
自20世纪初发现等离子体以来，已经取得了很大进展。第一种等离子体形式是热等离子体，由于对活细胞有潜在的热损伤，其在医学用途上受到限制。在20世纪后期，随着一种名为冷等离子体的非热大气等离子体的发展，深入的临床研究开始了，“等离子体医学”成为学术领域的一个新领域。等离子体开始主要用于环境问题，如水净化和废水处理，随后关于等离子体与液体相互作用的研究导致了“等离子体激活液体”（PAL）的诞生。PAL目前用于环境、食品、农业、纳米颗粒合成、分析化学和灭菌等领域。在医学领域，PAL的用途可以扩展到难以直接应用等离子体的地方。在这篇综述中，将介绍最近关于PAL的研究，以便让研究人员了解PAL在医学领域的应用计划和可能性。
