Non-Communicable Diseases Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Occupational Safety and Health Research Center, NICICO, World Safety Organization and Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Sci Rep. 2021 Dec 15;11(1):24071. doi: 10.1038/s41598-021-03377-7.
Headache has a variety of types, such as episodic primary headaches (EPH) and chronic primary headache (CPH) in its primary form. There is a positive correlation between these two types of headaches and hypertension (HTN), but in some works this correlation has been reported negatively. Therefore, we planned to study HTN-CPH as well as HTN-EPH correlation in our population. A sample of Rafsanjan population (10,000 individuals) entered the cohort study, as one of the Prospective Epidemiological Research Studies in Iran (PERSIAN). We compared the frequency of HTN categories in CPH and EPH cases with a normal population. Out of 9933 participants (46.6% males and 53.4% females) about 29% had EPH and 7.5% had CPH. HTN was found in 24.27% of EPH cases and 31.98% of CPH cases. HTN was also found to be associated with EPH and CPH in the crude model. Two Categories of HTN (Long controlled and uncontrolled) were not associated with EPH. On the other hand, CPH showed associations with all of the HTN categories. After included all variables and confounders, EPH and CPH had association with HTN without any considerable changes. There is strong HTN-EPH as well as HTN-CPH correlations in the studied population.
头痛有多种类型，如原发性发作性头痛 (EPH) 和原发性慢性头痛 (CPH)。这两种类型的头痛与高血压 (HTN) 之间存在正相关，但在某些研究中，这种相关性被报道为负相关。因此，我们计划在我们的人群中研究 HTN-CPH 以及 HTN-EPH 的相关性。拉夫桑詹人群 (10000 人) 的样本进入了队列研究，作为伊朗前瞻性流行病学研究 (PERSIAN) 的一部分。我们将 CPH 和 EPH 病例中 HTN 类别的频率与正常人群进行了比较。在 9933 名参与者中 (46.6%为男性，53.4%为女性)，约 29%患有 EPH，7.5%患有 CPH。在 EPH 病例中发现 HTN 占 24.27%，在 CPH 病例中占 31.98%。在原始模型中，HTN 也与 EPH 和 CPH 相关。高血压的两类 (长期控制和未控制) 与 EPH 无关。另一方面，CPH 与所有 HTN 类别均有关联。在纳入所有变量和混杂因素后，EPH 和 CPH 与 HTN 有关，没有明显变化。在研究人群中，HTN-EPH 和 HTN-CPH 之间存在很强的相关性。
