冠状动脉危险因素与临床胆囊疾病：预防胆结石的一种方法？
Coronary risk factors and clinical gallbladder disease: an approach to the prevention of gallstones?
作者信息
Diehl A K, Haffner S M, Hazuda H P, Stern M P
出版信息
Am J Public Health. 1987 Jul;77(7):841-5. doi: 10.2105/ajph.77.7.841.
Abstract
We examined the relationship of "coronary" risk factors to clinical gallbladder disease prevalence in a cross-sectional survey. Persons with hypercholesterolemia, hypertriglyceridemia, or low high-density-lipoprotein cholesterol levels had elevated risks for clinical gallbladder disease. Smokers of 20 pack-years or more and infrequent users of alcohol had increased risks, as did persons with hypertension or diabetes mellitus. After adjusting for age, body mass index, ethnicity, and the coronary variables, relationships persisted for diabetes in women (OR = 1.8) and frequent alcohol use in men (OR = 0.3). The proportion of gallbladder disease related to all coronary risk factors was estimated to be 52 per cent.
摘要
在一项横断面调查中，我们研究了“冠心病”危险因素与临床胆囊疾病患病率之间的关系。高胆固醇血症、高甘油三酯血症或高密度脂蛋白胆固醇水平低的人患临床胆囊疾病的风险升高。吸烟20包年及以上的人和不常饮酒的人患病风险增加，高血压或糖尿病患者也是如此。在对年龄、体重指数、种族和冠心病相关变量进行调整后，女性患糖尿病（OR = 1.8）和男性频繁饮酒（OR = 0.3）的关系依然存在。据估计，所有冠心病危险因素导致的胆囊疾病比例为52%。
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