Noitz Matthias, Steinkellner Christoph, Willingshofer Mark Philipp, Szasz Johannes, Dünser Martin
Dtsch Med Wochenschr. 2022 Jan;147(1-02):17-25. doi: 10.1055/a-1226-9091. Epub 2021 Dec 28.
The microcirculation includes all blood and lymph vessels with a diameter < 100 µm. Microcirculatory dysfunction is common in critically ill patients and is closely associated with both the severity of (multi-)organ dysfunction and mortality. The nature and extent of microcirculatory dysfunction differ depending on the underlying disease and are most pronounced in patients with systemic inflammation (e. g. sepsis), specific infections (e. g. malaria, dengue) or thrombocytopenia-associated multiple organ failure. This manuscript provides an overview of the pathophysiology, monitoring and therapy of microcirculatory dysfunction in the critically ill patient.
微循环包括所有直径小于100微米的血管和淋巴管。微循环功能障碍在重症患者中很常见，并且与（多）器官功能障碍的严重程度和死亡率密切相关。微循环功能障碍的性质和程度因潜在疾病而异，在全身性炎症（如脓毒症）、特定感染（如疟疾、登革热）或血小板减少相关的多器官功能衰竭患者中最为明显。本文概述了重症患者微循环功能障碍的病理生理学、监测和治疗。
