常染色体显性遗传性阿尔茨海默病：脑葡萄糖代谢
Dominantly inherited Alzheimer's disease: cerebral glucose metabolism.
作者信息
Polinsky R J, Noble H, Di Chiro G, Nee L E, Feldman R G, Brown R T
出版信息
J Neurol Neurosurg Psychiatry. 1987 Jun;50(6):752-7. doi: 10.1136/jnnp.50.6.752.
Abstract
Cerebral glucose metabolic rate (CMRGlu), measured by positron emission tomography, was bilaterally and symmetrically reduced in two patients with autosomal dominant Alzheimer's disease. Supramarginal gyri and temporal lobes were most severely affected. An isolated reduction of CMRGlu in the left supramarginal gyrus was observed in one asymptomatic at-risk subject.
摘要
通过正电子发射断层扫描测量的脑葡萄糖代谢率（CMRGlu）在两名常染色体显性阿尔茨海默病患者中双侧对称降低。缘上回和颞叶受影响最为严重。在一名无症状高危受试者中观察到左侧缘上回CMRGlu单独降低。
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