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静电镊子用于液滴操控。

Electrostatic tweezer for droplet manipulation.

机构信息

Department of Mechanical Engineering, City University of Hong Kong, Kowloon, Hong Kong Special Administrative Region 999077, People's Republic of China.

Institute of Microelectronics, Chinese Academy of Sciences, Beijing 100029, People's Republic of China.

出版信息

Proc Natl Acad Sci U S A. 2022 Jan 11;119(2). doi: 10.1073/pnas.2105459119.

Abstract

Various physical tweezers for manipulating liquid droplets based on optical, electrical, magnetic, acoustic, or other external fields have emerged and revolutionized research and application in medical, biological, and environmental fields. Despite notable progress, the existing modalities for droplet control and manipulation are still limited by the extra responsive additives and relatively poor controllability in terms of droplet motion behaviors, such as distance, velocity, and direction. Herein, we report a versatile droplet electrostatic tweezer (DEST) for remotely and programmatically trapping or guiding the liquid droplets under diverse conditions, such as in open and closed spaces and on flat and tilted surfaces as well as in oil medium. DEST, leveraging on the coulomb attraction force resulting from its electrostatic induction to a droplet, could manipulate droplets of various compositions, volumes, and arrays on various substrates, offering a potential platform for a series of applications, such as high-throughput surface-enhanced Raman spectroscopy detection with single measuring time less than 20 s.

摘要

各种基于光、电、磁、声或其他外部场的物理镊子已经出现,并彻底改变了医学、生物和环境领域的研究和应用。尽管已经取得了显著的进展,但现有的液滴控制和操作模式仍然受到额外响应添加剂的限制,并且在液滴运动行为方面的可控性相对较差,例如距离、速度和方向。在这里,我们报告了一种多功能的液滴静电镊子(DEST),可以在各种条件下远程和编程地捕获或引导液滴,例如在开放和封闭空间、平面和倾斜表面以及油介质中。DEST 利用其对液滴的静电感应产生的库仑吸引力,可以操纵各种成分、体积和排列的液滴在各种基底上,为一系列应用提供了一个潜在的平台,例如具有单个测量时间小于 20 s 的高通量表面增强拉曼光谱检测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a71/8764671/6277e6b5e634/pnas.2105459119fig01.jpg

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