Storr J, Lenney C A, Lenney W
Arch Dis Child. 1986 Mar;61(3):270-3. doi: 10.1136/adc.61.3.270.
Twenty nine young children with severe recurrent asthma were given nebulised beclomethasone dipropionate or normal saline in a double blind manner over a six month period. Progress was monitored using diary score cards. Those receiving beclomethasone had lower symptom scores, had more symptom free days, and required less additional treatment with bronchodilator agents. The code needed to be broken more frequently if normal saline was used. Over the study period height and weight increases in the two groups were similar, and no serious side effects were noted.
29名患有严重复发性哮喘的幼儿在6个月的时间里以双盲方式接受了雾化丙酸倍氯米松或生理盐水治疗。使用日记评分卡监测进展情况。接受丙酸倍氯米松治疗的患儿症状评分较低,无症状天数更多,并且需要使用支气管扩张剂进行额外治疗的次数更少。如果使用生理盐水,则需要更频繁地破解密码。在研究期间,两组儿童的身高和体重增长相似,且未观察到严重的副作用。