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类黄酮的生物技术应用和促进健康的特性:更新的视角。

Biotechnological Applications and Health-Promoting Properties of Flavonols: An Updated View.

机构信息

Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, 98125 Messina, Italy.

Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, V.le F. Stagno d'Alcontres 31, 98166 Messina, Italy.

出版信息

Int J Mol Sci. 2022 Feb 1;23(3):1710. doi: 10.3390/ijms23031710.

DOI:10.3390/ijms23031710
PMID:35163632
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8835978/
Abstract

Flavonols are a subclass of natural flavonoids characterized by a remarkable number of biotechnological applications and health-promoting properties. They attract researchers' attention due to many epidemiological studies supporting their usage. They are phytochemicals commonly present in our diet, being ubiquitous in the plant kingdom and, in particular, relatively very abundant in fruits and vegetables. All these aspects make flavonols candidates of choice for the valorization of products, based on the presence of a remarkable number of different chemical structures, each one characterized by specific chemical features capable of influencing biological targets inside the living organisms in very different manners. In this review, we analyzed the biochemical and physiological characteristics of flavonols focalizing our attention on the most promising compounds to shed some light on their increasing utilization in biotechnological applications in processing industries, as well as their suitable employment to improve the overall wellness of the humankind.

摘要

类黄酮是天然类黄酮的一个子类,具有许多生物技术应用和促进健康的特性。由于许多流行病学研究支持它们的使用,它们引起了研究人员的注意。它们是我们饮食中常见的植物化学物质,在植物界中无处不在,特别是在水果和蔬菜中相对非常丰富。所有这些方面都使类黄酮成为基于存在大量不同化学结构的产品增值的首选候选物,每种化学结构都具有特定的化学特征,能够以非常不同的方式影响生物体内部的生物靶标。在这篇综述中,我们分析了类黄酮的生化和生理特性,重点关注最有前途的化合物,以期阐明它们在加工工业中的生物技术应用中的日益广泛应用,以及它们在提高人类整体健康方面的适宜应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97a1/8835978/1e15a357eaf8/ijms-23-01710-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97a1/8835978/227c1c5c744f/ijms-23-01710-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97a1/8835978/1e15a357eaf8/ijms-23-01710-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97a1/8835978/227c1c5c744f/ijms-23-01710-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97a1/8835978/1e15a357eaf8/ijms-23-01710-g002.jpg

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2
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