von Wulffen H, Heesemann J, Bützow G H, Löning T, Laufs R
J Clin Microbiol. 1986 Nov;24(5):716-20. doi: 10.1128/jcm.24.5.716-720.1986.
The association of Campylobacter pyloridis with antrum gastritis and peptic ulcers was described. We investigated antral biopsies from 180 patients who underwent gastroscopy. By culture or Gram stain or both, we found overall 98 (54%) of them to be positive for C. pyloridis. In the various groups the following percentages were found to be positive: normal antral mucosa 3% (n = 30); moderate superficial antrum gastritis, 49% (n = 83); severe superficial antrum gastritis, 86% (n = 44); duodenal ulcer, 83% (n = 54); and gastric ulcer, 72% (n = 18). A serological screening that used a complement fixation test yielded the following results: highest rates of positive complement fixation titers were seen in patients with severe gastritis and those with duodenal ulcers, both with 79%; the lowest incidence was in a group of 20 blood donors, with 5%. Positive complement fixation titers in gastritis patients also correlated well with characteristic patterns on immunoglobulin G and A immunoblots, while there was no specific reactivity observed on immunoglobulin M immunoblots.
有人描述了幽门弯曲菌与胃窦炎和消化性溃疡之间的关联。我们对180例接受胃镜检查的患者的胃窦活检组织进行了研究。通过培养或革兰氏染色或两者兼用，我们发现其中共有98例（54%）幽门弯曲菌呈阳性。在不同组中，发现呈阳性的百分比分别为：正常胃窦黏膜3%（n = 30）；中度浅表性胃窦炎，49%（n = 83）；重度浅表性胃窦炎，86%（n = 44）；十二指肠溃疡，83%（n = 54）；胃溃疡，72%（n = 18）。一项采用补体结合试验的血清学筛查得出了以下结果：补体结合滴度阳性率最高的是重度胃炎患者和十二指肠溃疡患者，均为79%；最低发生率出现在一组20名献血者中，为5%。胃炎患者补体结合滴度阳性也与免疫球蛋白G和A免疫印迹上的特征性模式密切相关，而在免疫球蛋白M免疫印迹上未观察到特异性反应。
