学龄前哮喘患者的缓释茶碱
Slow release theophylline in preschool asthmatics.
作者信息
Conway S P, Houlsby W T
出版信息
Arch Dis Child. 1986 Oct;61(10):1024-6. doi: 10.1136/adc.61.10.1024.
Abstract
A double blind crossover trial with active or placebo slow release theophylline (Slo-phyllin) in children with asthma aged up to 4 years is described. Although no difference in symptom scores was shown, other differences in favour of active treatment were noted. We conclude that this preparation is of benefit in the management of the wheezing preschool child. The value of symptom scores as an index of clinical improvement is discussed.
摘要
本文描述了一项针对4岁及以下哮喘儿童的双盲交叉试验，试验中使用了活性或安慰剂缓释茶碱（Slo-phyllin）。尽管症状评分未显示出差异，但注意到了有利于活性治疗的其他差异。我们得出结论，这种制剂对喘息性学龄前儿童的治疗有益。文中还讨论了症状评分作为临床改善指标的价值。
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本文引用的文献
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Controlled trial of slow-release aminophylline in childhood asthma: are short-term trials valid?儿童哮喘缓释氨茶碱对照试验：短期试验是否有效？
Br Med J (Clin Res Ed). 1982 Mar 20;284(6319):863-6. doi: 10.1136/bmj.284.6319.863.
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Spectrum of asthma in children. I. Clinical and physiological components.儿童哮喘的范围。I. 临床和生理组成部分。
Br Med J. 1973 Oct 6;4(5883):7-11. doi: 10.1136/bmj.4.5883.7.
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A sustained release theophylline preparation: efficacy in childhood asthma with low serum theophylline levels.
Ann Allergy. 1978 Apr;40(4):252-7.
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Comparison of cromoglycate (cromolyn) and theophylline in controlling symptoms of chronic asthma. A collaborative study.
Lancet. 1977 Feb 19;1(8008):381-5. doi: 10.1016/s0140-6736(77)92601-0.
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Perception of asthma.哮喘认知
Lancet. 1976 Apr 24;1(7965):882-4. doi: 10.1016/s0140-6736(76)92097-3.
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