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类黄酮:大自然的药物宝库。

Flavonoids: A Reservoir of Drugs from Nature.

机构信息

Department of Chemistry, Govt. Degree College, Beerwah-193411, JK, India.

Department of Higher Education, Govt. Degree College, JK, India.

出版信息

Mini Rev Med Chem. 2023;23(7):772-786. doi: 10.2174/1389557522666220420102545.

Abstract

Flavonoids are associated with many plants and dietary foods; their chemical study has always attracted the interest of chemists working in the area of natural products and synthetic chemistry. Research in phytochemistry has produced many useful drugs. The analogs of flavonoids exhibit anticancer, anti-tuberculosis, anti-diabetic, antiviral, antibacterial, antioxidant, anti-inflammatory, antiproliferative, anti-spermatogenic, and antipsychotic activities. This review article highlights flavonoids' significance and medicinal application and displays a comparative overview of the biological activities of flavonoids and flavonoid derivatives. It covers almost all necessary reports for future directions in drug discovery.

摘要

类黄酮与许多植物和膳食食物有关;它们的化学研究一直吸引着从事天然产物和合成化学领域的化学家的兴趣。植物化学研究产生了许多有用的药物。类黄酮的类似物具有抗癌、抗结核、抗糖尿病、抗病毒、抗菌、抗氧化、抗炎、抗增殖、抗精子发生和抗精神病活性。本文重点介绍了类黄酮的重要性和药用应用,并对类黄酮及其衍生物的生物活性进行了比较概述。它涵盖了几乎所有未来药物发现方向的必要报告。

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