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乳制品与 COVID-19 风险之间的关联。

The association between dairy products and the risk of COVID-19.

机构信息

Department of Clinical Nutrition, School of Nutrition and Food Science, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

Department of Health in Disasters and Emergencies, School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran.

出版信息

Eur J Clin Nutr. 2022 Nov;76(11):1583-1589. doi: 10.1038/s41430-022-01149-8. Epub 2022 Apr 29.

Abstract

BACKGROUND

The fast spread of the coronavirus disease 2019 (COVID-19) epidemic and its high mortality were quickly noticed by the health community. Dairy products have been recognized as part of a healthy diet that helps strengthen body immunity and prevent infections. The present study can provide a comprehensive picture of the associations between dairy products consumption and COVID-19 incidence.

METHODS

This study was undertaken on 8801 adults participants of Yazd Health Study (YaHS) and Taghzieh Mardom-e-Yazd (TAMIZ) study aged 20 to 70 years. Data on dietary intakes were obtained using a validated food frequency questionnaire (FFQ). Multivariable logistic regression analysis was used to assess the association between dairy consumption and COVID-19.

RESULT

Our finding indicated that moderate intake of total dairy (OR: 0.63, 95% CI 0.46-0.87, P-trend = 0.97) could reduce the odds of COVID-19 and higher intake of low-fat dairy products (OR: 0.51 CI: 0.37-0.69, p-trend < 0.001) and low-fat milk (OR: 0.47 CI: 0.35-0.64, p-trend < 0.001) had a protective effect on COVID-19 after adjusting for confounders. However, higher intake of high-fat-dairy-product (OR: 1.40 CI: 1.09-1.92, p-trend = 0.03), high-fat milk (OR: 1.54 CI: 1.20-1.97, p-trend < 0.001), total yogurt (OR: 1.40 CI: 1.04-1.89, p-trend = 0.01), cheese (OR: 1.80 CI: 1.27-2.56, p-trend = 0.001), and butter (OR: 1.80 CI: 1.04-3.11, p-trend = 0.02) were related to increase the odds of COVID-19.

CONCLUSIONS

Moderate intake of total dairy could reduce odds of COVID-19 by 37% and, a higher intake of low-fat dairy products had a protective role on COVID-19. Although our study has promising results, stronger clinical studies are needed.

摘要

背景

新冠病毒病(COVID-19)疫情的迅速传播及其高死亡率引起了卫生界的关注。乳制品已被认为是健康饮食的一部分,有助于增强身体免疫力和预防感染。本研究可以全面了解乳制品消费与 COVID-19 发病率之间的关系。

方法

本研究纳入了年龄在 20 至 70 岁的 8801 名 Yazd 健康研究(YaHS)和 Taghzieh Mardom-e-Yazd(TAMIZ)研究的成年人参与者。采用经过验证的食物频率问卷(FFQ)获取饮食摄入量数据。多变量逻辑回归分析用于评估乳制品消费与 COVID-19 之间的关联。

结果

我们的研究结果表明,适量摄入总乳制品(OR:0.63,95%CI:0.46-0.87,P 趋势=0.97)可以降低 COVID-19 的发病风险,而较高摄入低脂乳制品(OR:0.51,CI:0.37-0.69,p 趋势 <0.001)和低脂牛奶(OR:0.47,CI:0.35-0.64,p 趋势 <0.001)对 COVID-19 具有保护作用,调整混杂因素后。然而,较高摄入高脂肪乳制品(OR:1.40,CI:1.09-1.92,p 趋势=0.03)、高脂牛奶(OR:1.54,CI:1.20-1.97,p 趋势 <0.001)、总酸奶(OR:1.40,CI:1.04-1.89,p 趋势=0.01)、奶酪(OR:1.80,CI:1.27-2.56,p 趋势=0.001)和黄油(OR:1.80,CI:1.04-3.11,p 趋势=0.02)与 COVID-19 发病风险增加相关。

结论

适量摄入总乳制品可使 COVID-19 的发病风险降低 37%,而较高摄入低脂乳制品对 COVID-19 具有保护作用。尽管我们的研究结果有一定的前景,但仍需要更强有力的临床研究。

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