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从哺乳动物组织中清除A组链球菌细胞壁。

Elimination of group A streptococcal cell walls from mammalian tissues.

作者信息

Gilbart J, Fox A

出版信息

Infect Immun. 1987 Jun;55(6):1526-8. doi: 10.1128/iai.55.6.1526-1528.1987.

DOI:10.1128/iai.55.6.1526-1528.1987
PMID:3553006
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC260547/
Abstract

The precise levels in mammalian tissues of rhamnose (a constituent of the group-specific polysaccharide) and muramic acid (a constituent of peptidoglycan) at various times after systemic administration of streptococcal cell walls were noted for the first time. The extreme resistance of the streptococcal cell wall to degradation by mammalian enzymes can now be clearly appreciated. The results help explain the chronic nature of certain inflammatory diseases elicited by streptococcal cell wall debris.

摘要

首次记录了在全身给予链球菌细胞壁后的不同时间，哺乳动物组织中鼠李糖（群体特异性多糖的一种成分）和胞壁酸（肽聚糖的一种成分）的精确水平。现在可以清楚地认识到链球菌细胞壁对哺乳动物酶降解的极强抗性。这些结果有助于解释由链球菌细胞壁碎片引发的某些炎症性疾病的慢性性质。

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本文引用的文献

1
The metabolic fate of 14C-labeled peptidoglycan monomer in mice. I. Identification of the monomer and the corresponding pentapeptide in urine.14C标记的肽聚糖单体在小鼠体内的代谢命运。I. 尿液中单体及相应五肽的鉴定。
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Arthropathic properties related to the molecular weight of peptidoglycan-polysaccharide polymers of streptococcal cell walls.与链球菌细胞壁肽聚糖 - 多糖聚合物分子量相关的关节病特性。
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Muramic acid detection in mammalian tissues by gas-liquid chromatography-mass spectrometry.通过气液色谱-质谱联用技术检测哺乳动物组织中的胞壁酸。
Infect Immun. 1980 Aug;29(2):526-31. doi: 10.1128/iai.29.2.526-531.1980.
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Measurement of bacterial cell wall in tissues by solid-phase radioimmunoassay: correlation of distribution and persistence with experimental arthritis in rats.用固相放射免疫分析法测定组织中的细菌细胞壁：其分布和持久性与大鼠实验性关节炎的相关性
Infect Immun. 1982 Oct;38(1):127-35. doi: 10.1128/iai.38.1.127-135.1982.
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Treatment of experimental erosive arthritis in rats by injection of the muralytic enzyme mutanolysin.通过注射溶菌酶壁质酶治疗大鼠实验性侵蚀性关节炎。
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Persistence of group a streptococcal cell walls related to chronic inflammation of rabbit dermal connective tissue.A组链球菌细胞壁的持续存在与兔真皮结缔组织的慢性炎症相关。
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Modifications in the alditol acetate method for analysis of muramic acid and other neutral and amino sugars by capillary gas chromatography-mass spectrometry with selected ion monitoring.用于通过毛细管气相色谱-质谱联用选择离子监测法分析胞壁酸及其他中性糖和氨基糖的乙酰糖醇乙酸酯法的改进。
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Granulomatous enterocolitis induced in rats by purified bacterial cell wall fragments.纯化细菌细胞壁片段诱导大鼠发生的肉芽肿性小肠结肠炎。
Gastroenterology. 1985 Sep;89(3):587-95. doi: 10.1016/0016-5085(85)90455-x.
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Degradation of muramyl dipeptide by mammalian serum.哺乳动物血清对胞壁酰二肽的降解作用。
Infect Immun. 1985 Oct;50(1):320-1. doi: 10.1128/iai.50.1.320-321.1985.
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Uveitis and arthritis induced by systemic injection of streptococcal cell walls.
Invest Ophthalmol Vis Sci. 1986 Jun;27(6):921-5.