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CFVisual:一个用于绘制基因结构和蛋白质结构的交互式桌面平台。

CFVisual: an interactive desktop platform for drawing gene structure and protein architecture.

机构信息

School of Life Science, North China University of Science and Technology, Tangshan, 063210, Hebei, China.

School of Information Science and Technology, Yanching Institute of Technology, Langfang, 065000, Hebei, China.

出版信息

BMC Bioinformatics. 2022 May 13;23(1):178. doi: 10.1186/s12859-022-04707-w.

DOI:10.1186/s12859-022-04707-w
PMID:35562653
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9102596/
Abstract

BACKGROUND

When researchers perform gene family analysis, they often analyze the structural characteristics of the gene, such as the distribution of introns and exons. At the same time, characteristic structural analysis of amino acid sequence is also essential, for example, motif and domain features. Researchers often integrate these analyses into one image to dig out more information, but the tools responsible for this integration are lacking.

RESULTS

Here, we developed a tool (CFVisual) for drawing gene structure and protein architecture. CFVisual can draw the phylogenetic tree, gene structure, and protein architecture in one picture, and has rich interactive capabilities, which can meet the work needs of researchers. Furthermore, it also supports arbitrary stitching of the above analysis images. It has become a useful helper in gene family analysis. The CFVisual package was implemented in Python and is freely available from https://github.com/ChenHuilong1223/CFVisual/ .

CONCLUSION

CFVisual has been used by some researchers and cited by some articles. In the future, CFVisual will continue to serve as a good helper for researchers in the study of gene structure and protein architecture.

摘要

背景

当研究人员进行基因家族分析时,他们通常会分析基因的结构特征,如内含子和外显子的分布。同时,对氨基酸序列的特征结构分析也是必不可少的,例如模体和结构域特征。研究人员经常将这些分析整合到一个图像中以挖掘更多信息,但负责这种整合的工具却缺乏。

结果

在这里,我们开发了一种用于绘制基因结构和蛋白质结构的工具(CFVisual)。CFVisual 可以在一张图片中绘制系统发育树、基因结构和蛋白质结构,并且具有丰富的交互功能,可以满足研究人员的工作需求。此外,它还支持对上述分析图像的任意拼接。它已成为基因家族分析的有用助手。CFVisual 包是用 Python 实现的,可以从 https://github.com/ChenHuilong1223/CFVisual/ 免费获得。

结论

CFVisual 已经被一些研究人员使用,并被一些文章引用。未来,CFVisual 将继续作为研究人员研究基因结构和蛋白质结构的良好助手。

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