2nd Department of Gynecology, Medical University of Lublin, Jaczewskiego 8, 20-954 Lublin, Poland.
Department of Dental and Maxillofacial Radiology, Medical University of Lublin, ul. Chodźki 6, 20-093 Lublin, Poland.
Int J Environ Res Public Health. 2022 Apr 26;19(9):5284. doi: 10.3390/ijerph19095284.
Regenerative medicine combines elements of tissue engineering and molecular biology aiming to support the regeneration and repair processes of damaged tissues, cells and organs. The most commonly used preparation in regenerative medicine is platelet rich plasma (PRP) containing numerous growth factors present in platelet granularities. This therapy is increasingly used in various fields of medicine. This article is a review of literature on the use of PRP in gynecology and obstetrics. There is no doubt that the released growth factors and proteins have a beneficial effect on wound healing and regeneration processes. So far, its widest application is in reproductive medicine, especially in cases of thin endometrium, Asherman's syndrome, or premature ovarian failure (POF) but also in wound healing and lower urinary tract symptoms (LUTS), such as urinary incontinence or recurrent genitourinary fistula auxiliary treatment. Further research is, however, needed to confirm the effectiveness and the possibility of its application in many other disorders.
再生医学结合了组织工程学和分子生物学的元素,旨在支持受损组织、细胞和器官的再生和修复过程。再生医学中最常用的制剂是富含血小板的血浆(PRP),其中含有血小板颗粒中存在的许多生长因子。这种治疗方法在医学的各个领域越来越多地被使用。本文是一篇关于 PRP 在妇科和产科中应用的文献综述。毫无疑问,释放的生长因子和蛋白质对伤口愈合和再生过程有有益的影响。到目前为止,其最广泛的应用是在生殖医学中,特别是在薄子宫内膜、Asherman 综合征或卵巢早衰(POF)的情况下,但也在伤口愈合和下尿路症状(LUTS)中,如尿失禁或复发性尿生殖瘘的辅助治疗。然而,还需要进一步的研究来证实其在许多其他疾病中的有效性和应用可能性。