Cao Meng, Li Shu, Tang Yucheng, Zou Yu
Department of Physical Education, College of Physical Education, Shenzhen University, Shenzhen, China.
Department of Sport and Exercise Science, College of Education, Zhejiang University, Hangzhou, China.
Front Pediatr. 2022 May 12;10:887852. doi: 10.3389/fped.2022.887852. eCollection 2022.
Metabolic disorders are common among children and adolescents with obesity and are associated with insulin resistance, hyperlipidemia, hypertension, and other cardiovascular risk factors. High-intensity interval training (HIIT) is a time-efficient method to improve cardiometabolic health. We performed a meta-analysis to determine the effects of HIIT on glycolipid metabolism in children with metabolic disorders.
Meta-analyses were conducted to determine the effect of HIIT on glycolipid metabolism markers. Subgroup analysis with potential moderators was explored [i.e., training intensity standard and work/rest time ratio (WRR)].
Eighteen trials involving 538 participants were included. HIIT showed positive effects on glycolipid metabolism, such as triglyceride (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), blood glucose (BG), blood insulin (BI), and homeostasis model assessment (HOMA)-IR, when compared to the non-training control group (CON); in addition to BG ( = 0.257), the combined results of other indicators have high heterogeneity ( = 0.000). HIIT showed no superior effects when compared to moderate-intensity training (MIT). Subgroup analysis demonstrated that HIIT protocol with a WRR of 1:1 was superior to MIT for reducing TG and LDL-C and used %maximal aerobic speed (MAS) as the exercise intensity was superior to MIT for reducing TG. HIIT protocol used %heart rate (HR) as the exercise intensity was superior to MIT for increasing HDL-C, decreasing BI, and HOMA-IR.
HIIT improved glycolipid metabolism in children with metabolic disorders. WRR and training intensity can affect the intervention effects of HIIT.
[https://www.crd.york.ac.uk/], identifier [CRD42021291473].
代谢紊乱在肥胖儿童和青少年中很常见，且与胰岛素抵抗、高脂血症、高血压及其他心血管危险因素相关。高强度间歇训练（HIIT）是一种提高心脏代谢健康的省时方法。我们进行了一项荟萃分析，以确定HIIT对患有代谢紊乱的儿童糖脂代谢的影响。
进行荟萃分析以确定HIIT对糖脂代谢标志物的影响。探索了具有潜在调节因素的亚组分析[即训练强度标准和工作/休息时间比（WRR）]。
纳入了18项试验，涉及538名参与者。与非训练对照组（CON）相比，HIIT对糖脂代谢有积极影响，如甘油三酯（TG）、总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-C）、高密度脂蛋白胆固醇（HDL-C）、血糖（BG）、血胰岛素（BI）和稳态模型评估（HOMA）-IR；除BG（ = 0.257）外，其他指标的合并结果具有高度异质性（ = 0.000）。与中等强度训练（MIT）相比，HIIT没有显示出更优的效果。亚组分析表明，WRR为1:1的HIIT方案在降低TG和LDL-C方面优于MIT，以最大有氧速度百分比（%MAS）作为运动强度的HIIT方案在降低TG方面优于MIT。以心率百分比（%HR）作为运动强度的HIIT方案在增加HDL-C、降低BI和HOMA-IR方面优于MIT。
HIIT改善了患有代谢紊乱的儿童的糖脂代谢。WRR和训练强度会影响HIIT的干预效果。
