Department of Pediatrics, University of Florida College of Medicine, 1600 Archer Road, Box 100296, Gainesville, Florida, 32610; Department of Obstetrics and Gynecology, University of Florida College of Medicine, Gainesville, FL, USA; Department of Epidemiology, University of Florida College of Public Health and Health Professions and College of Medicine, Gainesville, FL, USA.
Emory University School of Medicine, Department of Gynecology and Obstetrics, Woodruff Memorial Research Building, 101 Woodruff Circle, Suite 4208, Atlanta, GA 30322, USA.
Infect Dis Clin North Am. 2022 Jun;36(2):423-433. doi: 10.1016/j.idc.2022.01.002. Epub 2022 Jan 31.
Pregnancy seems to be a risk factor for severe disease with COVID-19. Although SARS-CoV-2 intrauterine transmission seems to be rare, most studies show COVID-19 during pregnancy increases the risk for pregnancy complications, with higher risk among those with severe disease compared with those mildly affected. Studies suggest that COVID-19 vaccination during pregnancy is safe and effective. Antibodies to SARS-CoV-2 have been found in umbilical cord blood and breast milk following maternal vaccination, which might provide protection to the infant. However, vaccination rates during pregnancy remain low. Studies are needed to understand ways to address SARS-CoV-2 vaccine hesitancy among pregnant persons.
妊娠似乎是 COVID-19 重症的一个危险因素。虽然 SARS-CoV-2 宫内传播似乎很少见，但大多数研究表明，妊娠期间的 COVID-19 会增加妊娠并发症的风险，与轻症患者相比，重症患者的风险更高。研究表明，妊娠期间接种 COVID-19 疫苗是安全有效的。在母亲接种疫苗后，在脐血和母乳中发现了针对 SARS-CoV-2 的抗体，这可能为婴儿提供保护。然而，妊娠期间的疫苗接种率仍然很低。需要研究如何解决孕妇对 SARS-CoV-2 疫苗的犹豫。
