Sabancı Arife, Eltas Abubekir, Celik Betul, Otlu Barıs
Department of Periodontology, Inonu University, Malatya, Turkey.
Department of Periodontology, University of Health Science, Istanbul, Turkey.
J Oral Biol Craniofac Res. 2022 Jul-Aug;12(4):405-409. doi: 10.1016/j.jobcr.2022.05.007. Epub 2022 May 17.
Type 2 diabetes mellitus (T2DM) is an important systemic disease, predisposing patients to inflammatory conditions including periodontitis and peri-implantitis and negatively affects dental implant success through various mechanisms. This study aimed to compare clinical and microbiological findings of individuals with dental implants with or without T2DM.
A total of 82 dental implants which were in function >3 years, were involved. The participants were divided into 2 groups; T2DM (n: 45 implants) and systemically healthy controls (n:37 implants). Periodontal indexes (Bleeding on probing (BOP), plaque index (PI), pocket depth (PD), and radiographic bone loss were recorded around implants in function >3 years. Subgingival microbiological samples were also collected from the peri-implant sites. Pathogens include , , , , , , , , , were evaluated.
Peri-implant heatlh was determined in systemically healthy (54.1%) and type 2 diabetes patients (24.4%). Peri-implantitis was also evident in systemically healthy (8.1%) and T2DM (35.6%) groups. No differences was found in shallow peri-implant pockets in both groups in terms of the prevelance of all evaluated bacteria (p > 0.05). However, , , and were isolated more frequently in deep peri-implant pockets in systemically healthy patients compared to T2DM patients (p < 0.05).
Evaluted periodontal pathogens may not be affected by the presence of T2DM in implants. T2DM may not significantly alter the levels of specific periodontal pathogens in shallow and deep peri-implant pockets. , and may be affected by T2DM in implants in deep pockets.
2型糖尿病（T2DM）是一种重要的全身性疾病，使患者易患包括牙周炎和种植体周围炎在内的炎症性疾病，并通过多种机制对牙种植体的成功产生负面影响。本研究旨在比较有或无T2DM的牙种植体患者的临床和微生物学 findings。
共纳入82颗功能超过3年的牙种植体。参与者分为2组；T2DM组（n：45颗种植体）和全身健康对照组（n：37颗种植体）。记录功能超过3年的种植体周围的牙周指数（探诊出血（BOP）、菌斑指数（PI）、牙周袋深度（PD）和影像学骨吸收）。还从种植体周围部位采集龈下微生物样本。评估病原体包括 ， ， ， ， ， ， ， ， ， 。
全身健康者（54.1%）和2型糖尿病患者（24.4%）确定了种植体周围健康。全身健康者（8.1%）和T2DM组（35.6%）也有种植体周围炎。两组浅种植体周围袋中所有评估细菌的患病率无差异（p > 0.05）。然而，与T2DM患者相比，全身健康患者的深种植体周围袋中 ， ， 和 的分离频率更高（p < 0.05）。
评估的牙周病原体可能不受种植体中T2DM的影响。T2DM可能不会显著改变浅、深种植体周围袋中特定牙周病原体的水平。 ， 和 可能受种植体中深袋T2DM的影响。
