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失眠和睡眠缺失对心血管疾病的影响。

The Effects of Insomnia and Sleep Loss on Cardiovascular Disease.

机构信息

Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA; Department of Neurology, The Ohio State University, Columbus, OH, USA.

Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.

出版信息

Sleep Med Clin. 2022 Jun;17(2):193-203. doi: 10.1016/j.jsmc.2022.02.008.

DOI:10.1016/j.jsmc.2022.02.008
PMID:35659073
Abstract

Sleep loss has negative impacts on quality of life, mood, cognitive function and heath. Insomnia or difficulty sleeping is also a prevalent issue, affecting up to 35% of the population at some point in their lives. Insomnia is linked to poor mood, increased use of health care resources, and decreased quality of life as well as possible links to cardiovascular risk factors and disease. Studies have shown an increase in cortisol levels, decreased immunity, and increased markers of sympathetic activity in sleep-deprived healthy subjects and those with chronic insomnia. The literature also shows that subjective complaints consistent with chronic insomnia and shortened sleep time, both independently and in combination, can be associated with the development of diabetes, hypertension, and cardiovascular disease. In this article, we will explore the relationship and strength of association between insufficient sleep and insomnia with these health conditions.

摘要

睡眠不足会对生活质量、情绪、认知功能和健康产生负面影响。失眠或难以入睡也是一个普遍存在的问题,在某些时候会影响高达 35%的人口。失眠与情绪不佳、更多地使用医疗保健资源以及生活质量下降有关,也可能与心血管风险因素和疾病有关。研究表明,在睡眠不足的健康受试者和慢性失眠患者中,皮质醇水平升高、免疫力下降以及交感神经活动标志物增加。文献还表明,与慢性失眠和睡眠时间缩短相一致的主观抱怨,无论是单独存在还是组合存在,都可能与糖尿病、高血压和心血管疾病的发生有关。在本文中,我们将探讨睡眠不足和失眠与这些健康状况之间的关系和关联强度。

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