Innovation Centre in Agritechnology, Universiti Teknologi Malaysia, Muar 84600, Malaysia.
Faculty of Engineering, School of Chemical and Energy Engineering, Universiti Teknologi Malaysia, Skudai 81300, Malaysia.
Molecules. 2022 May 26;27(11):3450. doi: 10.3390/molecules27113450.
() is a flowering tree best known for its essential oil, which has long been used as a fragrance ingredient for perfume and cosmetics. In addition, the plant has been used in traditional medicine in Asia and dates back hundreds of years. To date, there is a limited number of publications on the bioactivities of , which focused on its tyrosinase inhibition, antimicrobial, antidiabetic, anti-inflammatory, and antioxidant activities. Nevertheless, may have additional unexplored bioactivities associated with its bioactive compounds such as linalool (72.8% in flower oil and 80.1% in leaf oil), α-terpineol (6.04% flower oil), phenylethyl alcohol (2.58% flower oil), β-pinene (2.39% flower oil), and geraniol (1.23% flower oil). Notably, these compounds have previously been reported to exhibit therapeutic activities such as anti-cancer, anti-inflammation, anti-depression, anti-ulcer, anti-hypertriglyceridemia, and anti-hypertensive activities. In this review paper, we examine and discuss the scientific evidence on the phytochemistry, bioactivities, and traditional uses of . Here, we report a total of 168 biological compounds and highlight the therapeutic potential of its key bioactive compounds. This review may provide insights into the therapeutic potential of and its biologically active components for the prevention and treatment of diseases and management of human health and wellness.
（）是一种开花乔木，以其精油而闻名，这种精油长期以来一直被用作香水和化妆品的香料成分。此外，这种植物在亚洲传统医学中已经使用了数百年。迄今为止，关于 的生物活性的出版物数量有限，这些研究主要集中在其对酪氨酸酶的抑制作用、抗菌、抗糖尿病、抗炎和抗氧化活性上。尽管如此， 可能还有其他尚未被探索的与生物活性化合物相关的生物活性，如芳樟醇（花油中占 72.8%，叶油中占 80.1%）、α-松油醇（花油中占 6.04%）、苯乙醇（花油中占 2.58%）、β-蒎烯（花油中占 2.39%）和香叶醇（花油中占 1.23%）。值得注意的是，这些化合物以前曾被报道具有治疗活性，如抗癌、抗炎、抗抑郁、抗溃疡、抗高甘油三酯血症和抗高血压活性。在这篇综述论文中，我们检查和讨论了 的植物化学、生物活性和传统用途的科学证据。在这里，我们总共报告了 168 种生物化合物，并强调了其关键生物活性化合物的治疗潜力。这篇综述可能为 及其生物活性成分在预防和治疗疾病以及管理人类健康和健康方面的治疗潜力提供了一些见解。
