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理解口罩佩戴与传染病共演化:网络视角。

Understanding the coevolution of mask wearing and epidemics: A network perspective.

机构信息

Department of Computer Science, University of Virginia, Charlottesville, VA 22904.

Network Systems Science and Advanced Computing Division, Biocomplexity Institute, University of Virginia, Charlottesville, VA 22904.

出版信息

Proc Natl Acad Sci U S A. 2022 Jun 28;119(26):e2123355119. doi: 10.1073/pnas.2123355119. Epub 2022 Jun 22.

Abstract

Nonpharmaceutical interventions (NPIs) such as mask wearing can be effective in mitigating the spread of infectious diseases. Therefore, understanding the behavioral dynamics of NPIs is critical for characterizing the dynamics of disease spread. Nevertheless, standard infection models tend to focus only on disease states, overlooking the dynamics of "beneficial contagions," e.g., compliance with NPIs. In this work, we investigate the concurrent spread of disease and mask-wearing behavior over multiplex networks. Our proposed framework captures both the competing and complementary relationships between the dueling contagion processes. Further, the model accounts for various behavioral mechanisms that influence mask wearing, such as peer pressure and fear of infection. Our results reveal that under the coupled disease-behavior dynamics, the attack rate of a disease-as a function of transition probability-exhibits a critical transition. Specifically, as the transmission probability exceeds a critical threshold, the attack rate decreases abruptly due to sustained mask-wearing responses. We empirically explore the causes of the critical transition and demonstrate the robustness of the observed phenomena. Our results highlight that without proper enforcement of NPIs, reductions in the disease transmission probability via other interventions may not be sufficient to reduce the final epidemic size.

摘要

非药物干预(NPIs),如佩戴口罩,可以有效减缓传染病的传播。因此,了解 NPI 的行为动态对于刻画疾病传播的动态至关重要。然而,标准的传染病模型往往只关注疾病状态,而忽略了“有益的传染病”的动态,例如对 NPI 的遵守。在这项工作中,我们研究了在多重网络上疾病和口罩佩戴行为的同时传播。我们提出的框架捕捉了这两个竞争和互补的传染病过程之间的关系。此外,该模型考虑了影响戴口罩的各种行为机制,如同伴压力和对感染的恐惧。我们的结果表明,在耦合的疾病-行为动力学下,疾病的攻击率(作为转移概率的函数)表现出一个关键的转变。具体来说,当传播概率超过一个临界阈值时,由于持续的口罩佩戴反应,攻击率会突然下降。我们实证研究了关键转变的原因,并证明了观察到的现象具有稳健性。我们的结果强调,如果不适当执行 NPI,通过其他干预措施降低疾病传播概率可能不足以减少最终的疫情规模。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8813/9245665/f68885b97a75/pnas.2123355119fig01.jpg

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