Yuan Zhuoqun, Yang Di, Yang Zihan, Zhao Jingzhu, Liang Yanmei
Institute of Modern Optics, Nankai University, Tianjin Key Laboratory of Micro-scale Optical Information Science and Technology, Tianjin 300350, China.
Contributed equally.
Biomed Opt Express. 2022 Apr 25;13(5):3005-3020. doi: 10.1364/BOE.453326. eCollection 2022 May 1.
We present a deep learning-based digital refocusing approach to extend depth of focus for optical coherence tomography (OCT) in this paper. We built pixel-level registered pairs of low-resolution (LR) and high-resolution (HR) OCT images based on experimental data and introduced the receptive field block into the generative adversarial networks to learn the complex mapping relationship between LR-HR image pairs. It was demonstrated by results of phantom and biological samples that the lateral resolutions of OCT images were improved in a large imaging depth clearly. We firmly believe deep learning methods have broad prospects in optimizing OCT imaging.
在本文中,我们提出了一种基于深度学习的数字重聚焦方法,以扩展光学相干断层扫描(OCT)的焦深。我们基于实验数据构建了低分辨率(LR)和高分辨率(HR)OCT图像的像素级配准对,并将感受野模块引入生成对抗网络,以学习LR-HR图像对之间的复杂映射关系。体模和生物样本的结果表明,OCT图像的横向分辨率在较大成像深度上得到了显著提高。我们坚信深度学习方法在优化OCT成像方面具有广阔的前景。