Phase estimation for investigating the optical and mechanical properties of Monocryl suture for soft tissue approximation and ligation.

Monocryl is a bio-absorbable suture composed of a polyglycolide and poly-epsiloncaprolactone copolymer material and is considered a promising candidate for soft tissues approximation. Consequently, the physical, mechanical, and morphological properties are essential for the surgeons to select the suitable suture for their surgical perform. In this article, Mach Zehnder interferometer equipped with a mechanical drawing device are used for evaluating the mechanical properties and a better understanding of how the Monocryl suture reacts to loading. The two-dimensional fast Fourier transform is applied to extract the phase from the captured interference microinterferograms at different draw ratios. The extracted phase helps to determine some opto-mechanical and structural properties of Monocryle suture. Quantitative structure-activity relationships model is employed for investigating the biological activity of the tested suture. The stress-strain behavior of Monocryl suture has a J-shaped behavior which compatible with the behavior of the soft tissues. The molecular electrostatic potential maps showed that Monocryl model structure is proved to be electrophilic interplays.