Physics Department, Faculty of Science, Mansoura University, Mansoura, Egypt.
Microsc Res Tech. 2022 Oct;85(10):3455-3465. doi: 10.1002/jemt.24201. Epub 2022 Jul 8.
Monocryl is a bio-absorbable suture composed of a polyglycolide and poly-epsiloncaprolactone copolymer material and is considered a promising candidate for soft tissues approximation. Consequently, the physical, mechanical, and morphological properties are essential for the surgeons to select the suitable suture for their surgical perform. In this article, Mach Zehnder interferometer equipped with a mechanical drawing device are used for evaluating the mechanical properties and a better understanding of how the Monocryl suture reacts to loading. The two-dimensional fast Fourier transform is applied to extract the phase from the captured interference microinterferograms at different draw ratios. The extracted phase helps to determine some opto-mechanical and structural properties of Monocryle suture. Quantitative structure-activity relationships model is employed for investigating the biological activity of the tested suture. The stress-strain behavior of Monocryl suture has a J-shaped behavior which compatible with the behavior of the soft tissues. The molecular electrostatic potential maps showed that Monocryl model structure is proved to be electrophilic interplays.
单乔是一种由聚乙醇酸和聚己内酯共聚物材料组成的可生物吸收缝线，被认为是软组织接近的有前途的候选物。因此，物理、机械和形态学特性对于外科医生选择适合他们手术的缝线至关重要。在本文中，配备机械绘图装置的马赫-曾德尔干涉仪用于评估机械性能，并更好地了解单乔缝线对加载的反应。二维快速傅里叶变换用于从不同拉伸比下捕获的干涉微干涉图中提取相位。提取的相位有助于确定单乔缝线的一些光机械和结构特性。定量构效关系模型用于研究测试缝线的生物学活性。单乔缝线的应力-应变行为呈 J 形，与软组织的行为兼容。分子静电势能图表明，单乔模型结构被证明具有亲电性相互作用。
