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. 多糖的结构特征、抗氧化和降血糖活性。

Structural Characteristics, Antioxidant and Hypoglycemic Activities of Polysaccharide from .

机构信息

School of Food and Biological Engineering, Shaanxi University of Science and Technology, Xi'an 710021, China.

School of Chemistry and Chemical Engineering, Xi'an University of Science and Technology, Xi'an 710054, China.

出版信息

Molecules. 2022 Jun 29;27(13):4192. doi: 10.3390/molecules27134192.

Abstract

The structural characterization, the in vitro antioxidant activity, and the hypoglycemic activity of a polysaccharide (SGP-1-1) isolated from (SG) were studied in this paper. SGP-1-1, whose molecular weight is 19.037 kDa, consisted of Gal:Man:Glc in the molar ratio of 1:2.56:4.90. According to the results of methylation analysis, GC-MS, and NMR, HSQC was interpreted as a glucomannan with a backbone composed of 4)--D-Glc-(1→4)-, -D-Glc-(1→4)-, and 4)-Man-(1 residues. -1,6 linked an -D-Gal branch, and -1,6 linked an -D-Glc branch. The study indirectly showed that SGP-1-1 has good in vitro hypoglycemic and antioxidant activities and that these activities may be related to the fact that the SGP-1-1's monosaccharide composition (a higher proportion of Gal and Man) is the glycosidic-bond type (- and -glycosidic bonds). SGP-1-1 could be used as a potential antioxidant and hypoglycemic candidate for functional and nutritional food applications.

摘要

本文研究了从 (SG)中分离得到的多糖(SGP-1-1)的结构特征、体外抗氧化活性和降血糖活性。SGP-1-1 的分子量为 19.037 kDa,由 Gal:Man:Glc 以摩尔比 1:2.56:4.90 组成。根据甲基化分析、GC-MS 和 NMR 的结果,HSQC 被解释为一种葡甘露聚糖,其主链由 4)--D-Glc-(1→4)-、-D-Glc-(1→4)-和 4)-Man-(1 残基组成。-1,6 连接着一个 -D-Gal 支链,-1,6 连接着一个 -D-Glc 支链。研究间接表明,SGP-1-1 具有良好的体外降血糖和抗氧化活性,这些活性可能与 SGP-1-1 的单糖组成(Gal 和 Man 的比例较高)有关,其糖苷键类型为(-和--糖苷键)。SGP-1-1 可作为功能性和营养食品应用的潜在抗氧化和降血糖候选物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a99/9268605/b8bf9f8a02f3/molecules-27-04192-g001a.jpg

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