蛋白质摄入与老年人肌肉减少症：系统评价和荟萃分析。
Protein Intake and Sarcopenia in Older Adults: A Systematic Review and Meta-Analysis.
机构信息
Department of Geriatrics and Orthopedics, Università Cattolica del Sacro Cuore, L.go F. Vito 1, 00168 Rome, Italy.
Fondazione Policlinico Universitario "Agostino Gemelli" IRCCS, L.go A. Gemelli 8, 00168 Rome, Italy.
出版信息
Int J Environ Res Public Health. 2022 Jul 18;19(14):8718. doi: 10.3390/ijerph19148718.
BACKGROUND
The present systematic review and meta-analysis investigated the cross-sectional and longitudinal associations between protein intake and sarcopenia in older adults.
METHODS
Observational studies that investigated the association between protein intake and sarcopenia as the primary or secondary outcome in people aged 60 years and older were included. Studies published in languages other than English, Italian, Portuguese, and Spanish were excluded. Studies were retrieved from MEDLINE, SCOPUS, EMBASE, CINAHL, AgeLine, and Food Science Source databases through January 31, 2022. A pooled effect size was calculated based on standard mean differences.
RESULTS
Five cross-sectional studies, one longitudinal study, and one case-control study that investigated 3353 community-dwelling older adults with a mean age of approximately 73 years were included. The meta-analysis of four studies indicated that older adults with sarcopenia consumed significantly less protein than their peers with no sarcopenia.
CONCLUSIONS
Results of the present study suggest that an inadequate protein intake might be associated with sarcopenia in older adults.
背景
本系统评价和荟萃分析调查了蛋白质摄入量与老年人肌肉减少症之间的横断面和纵向关联。
方法
纳入了观察性研究，这些研究将蛋白质摄入量作为 60 岁及以上人群的主要或次要结局与肌肉减少症相关联。排除了非英语、意大利语、葡萄牙语和西班牙语发表的研究。研究通过 MEDLINE、SCOPUS、EMBASE、CINAHL、AgeLine 和 Food Science Source 数据库检索，截至 2022 年 1 月 31 日。基于标准均数差计算汇总效应量。
结果
纳入了 5 项横断面研究、1 项纵向研究和 1 项病例对照研究，共纳入了 3353 名平均年龄约为 73 岁的社区居住的老年人。四项研究的荟萃分析表明，患有肌肉减少症的老年人摄入的蛋白质明显少于没有肌肉减少症的同龄人。
结论
本研究结果表明，蛋白质摄入不足可能与老年人的肌肉减少症有关。
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